S100A7 promotes the development of human endometriosis by activating NF‐κB signaling pathway in endometrial stromal cells
Sign Up to like & getrecommendations! Published in 2021 at "Cell Biology International"
DOI: 10.1002/cbin.11578
Abstract: Endometriosis (EM) is a chronic inflammatory disease affecting women aged between 23 and 42 years with a prevalence of 6%–10%. S100A7, a member of the S100 protein family, has been implicated in promoting inflammation. However, the… read more here.
Keywords: endometriosis; stromal cells; endometrial stromal; expression ... See more keywords
LncRNA MALAT1 promotes decidualization of endometrial stromal cells via sponging miR‐498‐3p and targeting histone deacetylase 4
Sign Up to like & getrecommendations! Published in 2022 at "Cell Biology International"
DOI: 10.1002/cbin.11814
Abstract: Decidualization of human endometrial stromal cells (hESCs) is important for the maintenance of a successful pregnancy. Histone deacetylase 4 (HDAC4) was reported to be involved in the dysfunction of decidua‐derived mesenchymal stem cells. However, the… read more here.
Keywords: mir 498; endometrial stromal; hescs; hdac4 ... See more keywords
Novel EPC1 gene fusions in endometrial stromal sarcoma
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DOI: 10.1002/gcc.22649
Abstract: Endometrial stromal sarcoma encompasses a heterogeneous group of uterine mesenchymal neoplasms, which are currently divided into low‐grade and high‐grade subtypes. Low‐grade endometrial stromal sarcoma is morphologically bland; molecularly, these tumors frequently contain JAZF1‐SUZ12, JAZF1‐PHF1, and… read more here.
Keywords: gene fusions; novel epc1; grade; stromal sarcoma ... See more keywords
Expanding the molecular spectrum of gene fusions in endometrial stromal sarcoma: Novel subunits of the chromatin remodeling complexes PRC2 and NuA4/TIP60 as alternative fusion partners
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.1002/gcc.23109
Abstract: Endometrial stromal sarcomas (ESS) are morphologically and molecularly heterogeneous. We report novel gene fusions (EPC1::EED, EPC1::EZH2, ING3::PHF1) identified by targeted RNA sequencing in five cases. The ING3::PHF1‐fusion positive ESS presented in a 58‐year‐old female as… read more here.
Keywords: fusion; molecular spectrum; endometrial stromal; gene fusions ... See more keywords
Transcriptomic profiling analysis of human endometrial stromal cells treated with autologous platelet‐rich plasma
Sign Up to like & getrecommendations! Published in 2023 at "Reproductive Medicine and Biology"
DOI: 10.1002/rmb2.12498
Abstract: Abstract Purpose To clarify the mechanisms of intrauterine platelet‐rich plasma (PRP) infusion that support embryo implantation in in vitro fertilization treatment. Methods Blood and endometrial samples were collected from four infertile women. Human endometrial stromal… read more here.
Keywords: human endometrial; platelet rich; endometrial stromal; rich plasma ... See more keywords
Effects of a hyperandrogenaemic state on the proliferation and decidualization potential in human endometrial stromal cells
Sign Up to like & getrecommendations! Published in 2017 at "Archives of Gynecology and Obstetrics"
DOI: 10.1007/s00404-017-4295-y
Abstract: ObjectivePolycystic ovary syndrome (PCOS) is the most common endocrine disorder in women, involving hyperandrogenaemia and insulin resistance. Treatment options include dexamethasone, as well as the off-label use of metformin. To evaluate the impact of those… read more here.
Keywords: stromal cells; testosterone; effect; endometrial stromal ... See more keywords
Stimulation of chemokines in human endometrial stromal cells by tumor necrosis factor-α and interferon-γ is similar under apoptotic and non-apoptotic conditions
Sign Up to like & getrecommendations! Published in 2017 at "Archives of Gynecology and Obstetrics"
DOI: 10.1007/s00404-017-4586-3
Abstract: PurposeTumor necrosis factor (TNF)-α and interferon (IFN)-γ are pro-inflammatory cytokines which have been shown to be involved in the pathophysiology of implantation disorders. Both cytokines in combination are able to sensitize primarily resistant human endometrial… read more here.
Keywords: non apoptotic; stimulation; human endometrial; endometrial stromal ... See more keywords
ITRAQ-based proteomics analysis of tanshinone IIA on human ectopic endometrial stromal cells of adenomyosis
Sign Up to like & getrecommendations! Published in 2021 at "Archives of Gynecology and Obstetrics"
DOI: 10.1007/s00404-020-05936-1
Abstract: Adenomyosis is a diffuse or localized disease. Our previous study has indicated that tanshinone IIA (TSIIA) inhibits the proliferation, migration, and induces apoptosis of ectopic endometrial stromal cells (EESCs) of adenomyosis. However, the complex molecular… read more here.
Keywords: adenomyosis; stromal cells; differential proteins; tanshinone iia ... See more keywords
The expression and significance of leukemia inhibitory factor, interleukin-6 and vascular endothelial growth factor in Chinese patients with endometriosis
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DOI: 10.1007/s00404-021-05980-5
Abstract: To observe the levels of leukemia inhibitory factor (LIF), interleukin-6 (IL-6) and vascular endothelial growth factor (VEGF) in blood, peritoneal fluid, ectopic endometrial tissue, and ectopic endometrial stromal cells of patients with endometriosis, and to… read more here.
Keywords: lif vegf; stromal cells; group; endometrial stromal ... See more keywords
Low-grade endometrial stromal sarcoma with a novel MEAF6-SUZ12 fusion
Sign Up to like & getrecommendations! Published in 2019 at "Virchows Archiv"
DOI: 10.1007/s00428-019-02588-8
Abstract: Endometrial stromal sarcoma (ESS) is a rare mesenchymal neoplasm. Herein, we report a low-grade ESS with a novel MEAF6-SUZ12 fusion gene. A 40-year-old woman presented with a 9.0-cm abdominal wall mass juxtaposed to the postoperative… read more here.
Keywords: stromal sarcoma; grade ess; endometrial stromal; meaf6 ... See more keywords
MiR-182 inhibits proliferation, migration, invasion and inflammation of endometrial stromal cells through deactivation of NF-κB signaling pathway in endometriosis
Sign Up to like & getrecommendations! Published in 2021 at "Molecular and Cellular Biochemistry"
DOI: 10.1007/s11010-020-03986-2
Abstract: Endometriosis affects about 10-15% women for reproductive age, but it is not currently curable and the underlying etiology for this disease is still not clear. In the present study, functions and mechanisms of miR-182 and… read more here.
Keywords: proliferation migration; endometriosis; mir 182; stromal cells ... See more keywords