Endometriosis is associated with aberrant metabolite profiles in plasma.
Sign Up to like & getrecommendations! Published in 2017 at "Fertility and sterility"
DOI: 10.1016/j.fertnstert.2016.12.032
Abstract: OBJECTIVE To identify metabolites that are associated with and predict the presence of endometriosis. DESIGN Metabolomics study using state-of-the-art mass spectrometry approaches. SETTING University hospital and universities. PATIENT(S) Twenty-five women with laparoscopically confirmed endometriosis (cases)… read more here.
Keywords: endometriosis; mass spectrometry; endometriosis associated; associated aberrant ... See more keywords
Ethinylestradiol 20 μg/drospirenone 3 mg in a flexible extended regimen for the management of endometriosis-associated pelvic pain: a randomized controlled trial.
Sign Up to like & getrecommendations! Published in 2017 at "Fertility and sterility"
DOI: 10.1016/j.fertnstert.2017.07.1165
Abstract: OBJECTIVE To investigate the efficacy and safety of ethinylestradiol 20 μg/drospirenone 3 mg in a flexible extended regimen (FlexibleMIB) compared with placebo to treat endometriosis-associated pelvic pain (EAPP). DESIGN A phase 3, randomized, double-blind, placebo-controlled, parallel-group study,… read more here.
Keywords: endometriosis; phase; endometriosis associated; ethinylestradiol drospirenone ... See more keywords
Relugolix, an oral gonadotropin-releasing hormone receptor antagonist, reduces endometriosis-associated pain in a dose-response manner: a randomized, double-blind, placebo-controlled study.
Sign Up to like & getrecommendations! Published in 2020 at "Fertility and sterility"
DOI: 10.1016/j.fertnstert.2020.07.055
Abstract: OBJECTIVE To evaluate the efficacy and safety of three dose levels of relugolix, a gonadotropin-releasing hormone receptor antagonist, compared with placebo and leuprorelin in women with endometriosis-associated pain. DESIGN Phase 2, multicenter, randomized, double-blind, placebo-controlled… read more here.
Keywords: dose response; response manner; relugolix; associated pain ... See more keywords
Infiltrating T lymphocytes and programmed cell death protein-1/programmed death-ligand 1 expression in endometriosis-associated ovarian cancer.
Sign Up to like & getrecommendations! Published in 2021 at "Fertility and sterility"
DOI: 10.1016/j.fertnstert.2021.08.032
Abstract: OBJECTIVE To characterize T lymphocyte infiltration and programmed cell death protein-1 (PD-1)/programmed death-ligand 1 (PD-L1) expression in early-stage endometriosis-associated ovarian cancer (EAOC), ovarian endometriosis (OE), atypical endometriosis (AE), and deep endometriosis (DE). DESIGN Case-control, retrospective… read more here.
Keywords: endometriosis; death; endometriosis associated; ovarian cancer ... See more keywords
Endometriosis and cancer
Sign Up to like & getrecommendations! Published in 2019 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2018.12.015
Abstract: ABSTRACT Endometriosis, characterized by the presence of extra‐uterine endometrium, is a common gynecologic disorder in reproductive‐age women. Although the detailed molecular mechanism of etiology remains unelucidated, recent studies have gradually revealed both genetic and epigenetic… read more here.
Keywords: endometriosis; endometriosis associated; etiology; cancer ... See more keywords
Endometriosis-associated colorectal carcinosarcoma: A case report and review of the literature☆
Sign Up to like & getrecommendations! Published in 2021 at "Gynecologic Oncology Reports"
DOI: 10.1016/j.gore.2021.100696
Abstract: Highlights • Endometriosis associated intestinal tumors are rare, with 5 cases documented.• Endometriosis associated intestinal tumors might present like colorectal carcinoma.• Endometriosis associated intestinal Carcinoma is associated with poor prognosis. read more here.
Keywords: endometriosis; endometriosis associated; carcinosarcoma case; associated intestinal ... See more keywords
Genesis, genes and epigenetics of endometriosis-associated infertility
Sign Up to like & getrecommendations! Published in 2019 at "Nature Reviews Endocrinology"
DOI: 10.1038/s41574-019-0191-9
Abstract: Jae-Wook Jeong and colleagues report that histone deacetylase 3 (HDAC3) is downregulated in the endometrium of women with endometriosis. In addition, they show that the loss of HDAC3 is associated with aberrant hormonal signalling and… read more here.
Keywords: epigenetics endometriosis; endometriosis associated; genesis genes; genes epigenetics ... See more keywords
In the thicket of fears, doubts, and murky facts: some reflections on treatment modalities for endometriosis-associated pain.
Sign Up to like & getrecommendations! Published in 2023 at "Human reproduction"
DOI: 10.1093/humrep/dead061
Abstract: Endometriosis-associated pain can be managed by either surgery or hormonal therapy. The final decision as to which treatment modality to take is based on efficacy and possible complications of different treatment modalities, risk of recurrence,… read more here.
Keywords: thicket fears; associated pain; endometriosis associated; treatment ... See more keywords
Endometriosis-associated malignant transformation in abdominal surgical scar
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DOI: 10.1097/md.0000000000009136
Abstract: Background: Endometriosis-associated malignant transformation in abdominal surgical scar (EAMTAS) is a very rare and aggressive phenomenon. Our current article aims to provide a clinical overview, focusing on risk factors affecting survival. Methods: We performed a… read more here.
Keywords: transformation abdominal; associated malignant; endometriosis associated; malignant transformation ... See more keywords
Endometriosis-associated Ovarian Cancer is a Subset With a More Favorable Outcome and Distinct Clinical-pathologic Characteristics
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Gynecological Pathology"
DOI: 10.1097/pgp.0000000000000533
Abstract: There is a controversy about whether endometriosis-associated ovarian cancer (EAOC) might represent a different entity from the corresponding ovarian cancer occurring de novo, in the absence of endometriosis. This study investigated the clinical-pathologic characteristics and… read more here.
Keywords: endometriosis; endometriosis associated; ovarian cancer; associated ovarian ... See more keywords
Endometriosis-associated recto-sigmoid cancer: a case report
Sign Up to like & getrecommendations! Published in 2018 at "BMC Cancer"
DOI: 10.1186/s12885-018-4797-4
Abstract: BackgroundEndometriosis is a relatively common condition in women of reproductive age. Malignant transformation of intestinal endometriosis is a very rare event. We report a case in which a patient with a history of endometriosis underwent… read more here.
Keywords: endometriosis; endometriosis associated; case; report ... See more keywords