Melatonin inhibits endometriosis development by disrupting mitochondrial function and regulating tiRNAs
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Pineal Research"
DOI: 10.1111/jpi.12842
Abstract: Endometriosis is a benign gynecological disease characterized by abnormal growth of endometrial‐like cells outside the uterus. Melatonin, a hormone secreted by the pineal gland, has been shown to have therapeutic effects in various diseases, including… read more here.
Keywords: endometriosis; stromal cells; inhibits endometriosis; endometriosis development ... See more keywords
Genetic variations in UCA1, a lncRNA functioning as a miRNA sponge, determine endometriosis development and the potential associated infertility via regulating lipogenesis
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0271616
Abstract: Endometriosis is a hormone-associated disease which has been considered as the precursor for certain types of ovarian cancer. In recent years, emerging evidence demonstrated potent roles of lncRNA in regulating cancer development. Since endometriosis shares… read more here.
Keywords: via regulating; endometriosis; endometriosis development; genetic variations ... See more keywords
Inhibition of VEGFR1 TK Signaling in Peritoneal Macrophages Suppresses Endometriosis Development
Sign Up to like & getrecommendations! Published in 2025 at "In Vivo"
DOI: 10.21873/invivo.14059
Abstract: Background/Aim: Endometriosis is characterized by the accumulation of immune cells in endometrial lesions and the peritoneal cavity. Macrophages contribute to the growth and neovascularization of endometriotic lesions. Vascular endothelial growth factor receptor-1 (VEGFR1) is involved… read more here.
Keywords: endometriosis development; vegfr1 signaling; endometriosis; peritoneal macrophages ... See more keywords
Leptin Stimulates Endometriosis Development in Mouse Models
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10092160
Abstract: Endometriosis is a chronic inflammatory condition in women, and obesity leads to an inflammatory condition that is directly involved in the etiology of endometriosis. However, observational studies have shown an inverse correlation between endometriosis and… read more here.
Keywords: endometriosis development; control; mouse models; endometriosis ... See more keywords
Bioinformatics-based analysis of the roles of sex hormone receptors in endometriosis development
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Medical Sciences"
DOI: 10.7150/ijms.79516
Abstract: Endometriosis is a hormone-dependent disease in women of reproductive age and seriously affects women's health. To analyze the involvement of sex hormone receptors in endometriosis development, we performed bioinformatics analysis using four datasets derived from… read more here.
Keywords: hormone; endometriosis development; hormone receptors; sex hormone ... See more keywords