Repurposing the Homing Endonuclease I-SceI for Positive Selection and Development of Gene-Editing Technologies.
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DOI: 10.1021/acssynbio.1c00340
Abstract: Prokaryote genomes encode diverse programmable DNA endonucleases with significant potential for biotechnology and gene editing. However, these endonucleases differ significantly in their properties, which must be screened and measured. While positive selection screens based on… read more here.
Keywords: homing endonuclease; endonuclease scei; gene editing; positive selection ... See more keywords