Diketo acids inhibit the cap-snatching endonuclease of several Bunyavirales.
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DOI: 10.1016/j.antiviral.2020.104947
Abstract: Several fatal bunyavirus infections lack specific treatment. Here, we show that diketo acids engage a panel of bunyavirus cap-snatching endonucleases, inhibit their catalytic activity and reduce viral replication of a taxonomic representative in vitro. Specifically,… read more here.
Keywords: diketo acids; endonuclease several; inhibit cap; acids inhibit ... See more keywords