Cas9 endonuclease and off-target activity
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DOI: 10.1126/science.357.6350.467-q
Abstract: Genome Sequencing The RNA-guided endonuclease Cas9 has brought about a revolution in genetic engineering and genome editing. However, issues with the system include the off-target activity of the endonuclease and promiscuous cleavage, making accuracy in… read more here.
Keywords: cas9 endonuclease; endonuclease; target activity; endonuclease target ... See more keywords