Endophilin2 Interacts with GluA1 to Mediate AMPA Receptor Endocytosis Induced by Oligomeric Amyloid-β
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DOI: 10.1155/2017/8197085
Abstract: Amyloid-β (Aβ) plays an important role in Alzheimer's disease (AD), as oligomeric Aβ induces loss of postsynaptic AMPA receptors (AMPARs) leading to cognitive deficits. The loss of postsynaptic AMPARs is mediated through the clathrin-dependent endocytosis… read more here.
Keywords: endocytosis; ampar endocytosis; oligomeric induced; endophilin2 interacts ... See more keywords