Endoscopic remission assessed with PICaSSO virtual electronic chromendoscopy accurately predicts clinical outcomes in ulcerative colitis.
Sign Up to like & getrecommendations! Published in 2022 at "United European gastroenterology journal"
DOI: 10.1002/ueg2.12185
Abstract: BACKGROUND AND AIMS A composite endoscopic-histologic remission is increasingly explored as an important endpoint in ulcerative colitis (UC). We investigated combined endoscopic-histologic remission for predicting clinical outcomes at 12 months compared with endoscopic remission alone using… read more here.
Keywords: clinical outcomes; endoscopic remission; remission; histologic remission ... See more keywords
Endoscopy and histology in inflammatory bowel diseases patients: Complementary or alternatives?
Sign Up to like & getrecommendations! Published in 2022 at "United European Gastroenterology Journal"
DOI: 10.1002/ueg2.12202
Abstract: To date, endoscopic remission is the main therapeutic target in patients with ulcerative colitis (UC), influencing treatment decisions. However, growing evidence shows that subjects with endoscopic remission but persistent histological activity have an increased risk… read more here.
Keywords: histology; endoscopic remission; score; disease ... See more keywords
Ratio of submucosal thickness to total bowel wall thickness as a new sonographic parameter to estimate endoscopic remission of ulcerative colitis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Gastroenterology"
DOI: 10.1007/s00535-021-01847-3
Abstract: The development of feasible, reliable parameters and criteria for intestinal ultrasound (IUS) to estimate endoscopic remission of ulcerative colitis (UC) is a crucial clinical challenge. Such parameters must be simple, objective, and reproducible so that… read more here.
Keywords: parameter; estimate endoscopic; bowel wall; endoscopic remission ... See more keywords
Higher Mucosal Healing with Tumor Necrosis Factor Inhibitors in Combination with Thiopurines Compared to Methotrexate in Crohn’s Disease
Sign Up to like & getrecommendations! Published in 2018 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-018-5422-8
Abstract: BackgroundThe differential impact of anti-tumor necrosis factor (anti-TNF) therapy with methotrexate versus thiopurine co-therapy on endoscopic remission remains uncertain.AimsTo compare rates of endoscopic remission based on methotrexate or thiopurine co-therapy used with anti-TNF therapy in… read more here.
Keywords: methotrexate; thiopurine; anti tnf; therapy ... See more keywords
Infliximab Trough Levels Are Not Predictive of Relapse in Patients with IBD in Endoscopic Remission: A Multicenter Cohort Study
Sign Up to like & getrecommendations! Published in 2020 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-020-06645-0
Abstract: Therapeutic drug monitoring (TDM) is important in optimizing use of biologics in inflammatory bowel diseases (IBD). However, the role of proactive TDM during remission remains uncertain. This retrospective study included patients receiving infliximab (IFX) therapy… read more here.
Keywords: trough levels; remission; study; relapse ... See more keywords
DOP16 The ratio of submucosa thickness to the total bowel wall thickness can be a sonographic parameter to estimate endoscopic remission in Ulcerative Colitis
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Crohn's and Colitis"
DOI: 10.1093/ecco-jcc/jjab073.055
Abstract: A less invasive examination that can estimate endoscopic remission is needed. Intestinal ultrasound (IUS) is a promising option. The bowel wall thickness (BWT) is a widely-accepted objective parameter in IUS to assess colonic inflammation, but… read more here.
Keywords: bwt; endoscopic remission; thickness; remission ... See more keywords
Oral Vancomycin Induced and Maintained Clinical and Endoscopic Remission in Ulcerative Colitis and Primary Sclerosing Cholangitis Post-liver Transplantation.
Sign Up to like & getrecommendations! Published in 2023 at "Inflammatory bowel diseases"
DOI: 10.1093/ibd/izad040
Abstract: We present a case of a 34-year-old man with primary sclerosing cholangitis and associated ulcerative colitis refractory to multiple advanced therapies who achieved clinical and endoscopic remission with oral vancomycin therapy. read more here.
Keywords: endoscopic remission; oral vancomycin; sclerosing cholangitis; primary sclerosing ... See more keywords
Is Endoscopic Remission in Ulcerative Colitis Still Good Enough?
Sign Up to like & getrecommendations! Published in 2019 at "Inflammatory bowel diseases"
DOI: 10.1093/ibd/izz177
Abstract: Histology is a treatment target for investigational agents. Histologic activity predicts relapses and increased risk of colorectal neoplasia. Recent studies demonstrated that the proportion of patients achieving histologic improvement is low. Research is needed before… read more here.
Keywords: still good; remission ulcerative; colitis still; remission ... See more keywords
Modelling of the relationship between infliximab exposure, faecal calprotectin and endoscopic remission in patients with Crohn's disease
Sign Up to like & getrecommendations! Published in 2020 at "British Journal of Clinical Pharmacology"
DOI: 10.1111/bcp.14364
Abstract: Evidence for the benefits of pharmacokinetic (PK) and pharmacodynamic (PD) monitoring of infliximab in patients with Crohn's disease (CD) remains scarce. We aimed to develop a population (pop)PK/PD model to characterise the infliximab dose–exposure–biomarker–response (faecal… read more here.
Keywords: faecal calprotectin; infliximab; exposure; crohn disease ... See more keywords
Serum leucine‐rich alpha‐2 glycoprotein as a predictive factor of endoscopic remission in Crohn's disease
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Gastroenterology and Hepatology"
DOI: 10.1111/jgh.15907
Abstract: The usefulness of fecal calprotectin (FC) and serum leucine‐rich alpha‐2 glycoprotein (LRG) assessing the activity of Crohn's disease (CD) remains to be fully demonstrated in Asia. The present study aimed to elucidate whether FC and… read more here.
Keywords: serum leucine; endoscopic remission; leucine rich; crohn disease ... See more keywords
Clinical Efficacy of Probiotic Therapy on Bowel-Related Symptoms in Patients with Ulcerative Colitis during Endoscopic Remission: An Observational Study
Sign Up to like & getrecommendations! Published in 2022 at "Gastroenterology Research and Practice"
DOI: 10.1155/2022/9872230
Abstract: Background A substantial percentage of patients with ulcerative colitis (UC) have irritable bowel syndrome- (IBS-) like symptoms despite adequate treatment and endoscopic remission. In this study, we evaluated the clinical efficacy of probiotic therapy for… read more here.
Keywords: endoscopic remission; bowel; ibs like; remission ... See more keywords