The B cell response to both protein and nucleic acid antigens displayed on apoptotic cells are dependent on endosomal pattern recognition receptors.
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DOI: 10.1016/j.jaut.2020.102582
Abstract: In systemic autoimmune diseases such as systemic lupus erythematosus (SLE), B cell tolerance is lost and there is a production of autoantibodies that drive pathology. The specificities of these antibodies are towards a wide range… read more here.
Keywords: pattern recognition; endosomal pattern; recognition receptors; apoptotic cells ... See more keywords