The regulation of Endosomal Sorting Complex Required for Transport and accessory proteins in multivesicular body sorting and enveloped viral budding - An overview.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2019.01.015
Abstract: ESCRT (Endosomal Sorting Complex Required for Transport) machinery drives different cellular processes such as endosomal sorting, organelle biogenesis, vesicular trafficking, maintenance of plasma membrane integrity, membrane fission during cytokinesis and enveloped virus budding. The normal… read more here.
Keywords: multivesicular body; endosomal sorting; complex required; viral budding ... See more keywords
Endofin is required for HD-PTP and ESCRT-0 interdependent endosomal sorting of ubiquitinated transmembrane cargoes
Sign Up to like & getrecommendations! Published in 2021 at "iScience"
DOI: 10.1016/j.isci.2021.103274
Abstract: Summary Internalized and ubiquitinated signaling receptors are silenced by their intraluminal budding into multivesicular bodies aided by the endosomal sorting complexes required for transport (ESCRT) machinery. HD-PTP, an ESCRT protein, forms complexes with ESCRT-0, -I… read more here.
Keywords: ptp escrt; endofin required; endosomal sorting; endofin ... See more keywords
Plant ESCRT Complexes: Moving Beyond Endosomal Sorting.
Sign Up to like & getrecommendations! Published in 2017 at "Trends in plant science"
DOI: 10.1016/j.tplants.2017.08.003
Abstract: The endosomal sorting complex required for transport (ESCRT) machinery is an ancient system that deforms membrane and severs membrane necks from the inside. Extensive evidence has accumulated to demonstrate the conserved functions of plant ESCRTs… read more here.
Keywords: plant escrt; plant; endosomal sorting; escrt complexes ... See more keywords
Regulation of cargo transfer between ESCRT-0 and ESCRT-I complexes by flotillin-1 during endosomal sorting of ubiquitinated cargo
Sign Up to like & getrecommendations! Published in 2017 at "Oncogenesis"
DOI: 10.1038/oncsis.2017.47
Abstract: Ubiquitin-dependent sorting of membrane proteins in endosomes directs them to lysosomal degradation. In the case of receptors such as the epidermal growth factor receptor (EGFR), lysosomal degradation is important for the regulation of downstream signalling.… read more here.
Keywords: endosomal sorting; escrt; ubiquitinated cargo; escrt complexes ... See more keywords
TFG regulates secretory and endosomal sorting pathways in neurons to promote their activity and maintenance
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2210649119
Abstract: Significance Pathological mutations in TFG have been implicated in a variety of neurodegenerative diseases, including early-onset forms of hereditary spastic paraplegia (HSP). In this work, we demonstrate that the TFG p.R106C mutation, which has been… read more here.
Keywords: secretory endosomal; maintenance; regulates secretory; tfg ... See more keywords
Molecular interplays of the Entamoeba histolytica endosomal sorting complexes required for transport during phagocytosis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.855797
Abstract: Entamoeba histolytica, the causative agent of human amoebiasis, exhibits a continuous membrane remodelling to exert its virulence properties. During this dynamic process, the Endosomal Sorting Complexes Required for Transport (ESCRT) machinery is a key player,… read more here.
Keywords: required transport; histolytica; sorting complexes; entamoeba histolytica ... See more keywords
The endosomal sorting complex required for transport repairs the membrane to delay cell death
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.1007446
Abstract: The endosomal sorting complex required for transport (ESCRT) machinery plays a key role in the repair of damaged plasma membranes with puncta form and removes pores from the plasma membrane in regulated cell death, apoptosis,… read more here.
Keywords: cell; escrt iii; escrt; membrane ... See more keywords