A role for Rab30 in retrograde trafficking and maintenance of endosome-TGN organization.
Sign Up to like & getrecommendations! Published in 2020 at "Experimental cell research"
DOI: 10.1016/j.yexcr.2020.112442
Abstract: Rab30 is a poorly characterized small GTPase. Here we show that Rab30 is localized primarily to the TGN and recycling endosomes in a range of cell types, including primary neurons; minor levels of Rab30 were… read more here.
Keywords: rab30; endosome tgn; role rab30; tgn organization ... See more keywords
Rab7 palmitoylation is required for efficient endosome-to-TGN trafficking
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cell Science"
DOI: 10.1242/jcs.199729
Abstract: ABSTRACT Retromer is a multimeric protein complex that mediates endosome-to-trans-Golgi network (TGN) and endosome-to-plasma membrane trafficking of integral membrane proteins. Dysfunction of this complex has been linked to Alzheimer's disease and Parkinson's disease. The recruitment… read more here.
Keywords: endosome tgn; palmitoylation; tgn trafficking; efficient endosome ... See more keywords
Endosome-to-TGN Trafficking: Organelle-Vesicle and Organelle-Organelle Interactions
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2020.00163
Abstract: Retrograde transport from endosomes to the trans-Golgi network (TGN) diverts proteins and lipids away from lysosomal degradation. It is essential for maintaining cellular homeostasis and signaling. In recent years, significant advancements have been made in… read more here.
Keywords: endosome tgn; vesicle organelle; organelle vesicle; tgn trafficking ... See more keywords