Fusobacterium nucleatum mediates endothelial damage and increased permeability following single species and polymicrobial infection
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Periodontology"
DOI: 10.1002/jper.21-0671
Abstract: Abstract Background Numerous lines of evidence link periodontal pathobionts and their virulence factors with endothelial damage. Most research has been conducted using single species infections at the exclusion of other periodontal microorganisms that have been… read more here.
Keywords: infection; polymicrobial infection; endothelial damage; permeability ... See more keywords
Coagulopathy in patients with acute pulmonary embolism: a pilot study of whole blood coagulation and markers of endothelial damage
Sign Up to like & getrecommendations! Published in 2017 at "Scandinavian Journal of Clinical and Laboratory Investigation"
DOI: 10.1080/00365513.2016.1239130
Abstract: Abstract Whole blood coagulation and markers of endothelial damage were studied in patients with acute pulmonary embolism (PE), and evaluated in relation to PE severity. Twenty-five patients were enrolled prospectively each having viscoelastical analysis of… read more here.
Keywords: patients acute; blood; endothelial damage; blood coagulation ... See more keywords
Eosinopenia and increased markers of endothelial damage are characteristic of COVID-19 infection at time of hospital admission
Sign Up to like & getrecommendations! Published in 2022 at "Scandinavian Journal of Clinical and Laboratory Investigation"
DOI: 10.1080/00365513.2022.2079095
Abstract: Abstract In December 2019, a new virus has been discovered, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), leading to coronavirus disease 2019 (COVID-19). COVID-19 has been defined as an evolving disease with different phases. It… read more here.
Keywords: covid; markers endothelial; endothelial damage; infection time ... See more keywords
Impact of innate immunity, endothelial damage, and metabolic biomarkers on COVID-19 severity and mortality
Sign Up to like & getrecommendations! Published in 2022 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofac427
Abstract: Abstract In this study, abnormal levels of myeloid activation, endothelial damage and innate immune markers were associated with severe COVID-19, while higher levels of metabolic biomarkers (irisin, leptin), demonstrated a protective effect. These data support… read more here.
Keywords: metabolic biomarkers; damage; impact innate; immunity endothelial ... See more keywords
Bradykinin B1 receptor antagonist protects against cold stress–induced erectile dysfunction in rats
Sign Up to like & getrecommendations! Published in 2023 at "Sexual Medicine"
DOI: 10.1093/sexmed/qfac004
Abstract: Abstract Background Erectile dysfunction (ED) demonstrates seasonal variation with higher rates in winter, and we hypothesize that endothelial damage in erectile tissue caused by bradykinin receptor B1 (B1R) might be detrimental to this change. Aim… read more here.
Keywords: stress; cold stress; b1r; endothelial damage ... See more keywords
Endotheliopathy Is Induced by Plasma From Critically Ill Patients and Associated With Organ Failure in Severe COVID-19
Sign Up to like & getrecommendations! Published in 2020 at "Circulation"
DOI: 10.1161/circulationaha.120.050907
Abstract: This article assessed whether plasma collected from patients with COVID-19 at different disease stages could trigger endothelial damage in vitro by using cultured human pulmonary microvascular endothelial cells (HPMVEC) This study also further investigated the… read more here.
Keywords: ill patients; critically ill; endothelial damage; damage ... See more keywords
Hypoxia Increases the Potential for Neutrophil-mediated Endothelial Damage in Chronic Obstructive Pulmonary Disease
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Respiratory and Critical Care Medicine"
DOI: 10.1164/rccm.202006-2467oc
Abstract: Rationale Patients with chronic obstructive pulmonary disease (COPD) experience excess cardiovascular morbidity and mortality, and exacerbations further increase the risk of such events. COPD is associated with persistent blood and airway neutrophilia and systemic and… read more here.
Keywords: damage; obstructive pulmonary; chronic obstructive; hypoxia ... See more keywords
Endothelial damage in septic shock patients as evidenced by circulating syndecan-1, sphingosine-1-phosphate and soluble VE-cadherin: a substudy of ALBIOS
Sign Up to like & getrecommendations! Published in 2021 at "Critical Care"
DOI: 10.1186/s13054-021-03545-1
Abstract: Background Septic shock is characterized by breakdown of the endothelial glycocalyx and endothelial damage, contributing to fluid extravasation, organ failure and death. Albumin has shown benefit in septic shock patients. Our aims were: (1) to… read more here.
Keywords: septic shock; endothelial damage; sphingosine phosphate; cadherin ... See more keywords
Vascular endothelium function among male carriers of BRCA 1&2 germline mutation
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DOI: 10.18632/oncotarget.27118
Abstract: Background: Breast cancer susceptibility genes 1&2 (BRCA1&2) mutations hinder DNA-repair. Germline mutations in these genes are known to cause cancer; however, they may have other consequences. In this study we evaluated for the first time,… read more here.
Keywords: vascular endothelium; mutation positive; endothelial damage; function ... See more keywords
Antegrade cardioplegia as a possible cause of acute saphenous vein endothelial damage in patients undergoing on pump coronary artery bypass surgery.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of thoracic disease"
DOI: 10.21037/jtd.2018.06.91
Abstract: Background The administration of antegrade cardioplegia through vein grafts after the completion of each distal anastomosis is a common practice. However, the cardioplegic solution may disrupt the vein endothelium and contribute to late vein graft… read more here.
Keywords: antegrade cardioplegia; vein; pump coronary; endothelial damage ... See more keywords
MSC Transplantation Attenuates Inflammation, Prevents Endothelial Damage and Enhances the Angiogenic Potency of Endogenous MSCs in a Model of Pulmonary Arterial Hypertension
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Inflammation Research"
DOI: 10.2147/jir.s355479
Abstract: Purpose Pulmonary arterial hypertension (PAH) is a progressive and fatal pulmonary vascular disease initiated by endothelial dysfunction. Mesenchymal stromal cells (MSCs) have been shown to ameliorate PAH in various rodent models; however, these models do… read more here.
Keywords: pah; endothelial damage; msc transplantation; mscs ... See more keywords