Preparation and protective effects of 1,8‐cineole‐loaded self‐microemulsifying drug delivery system on lipopolysaccharide‐induced endothelial injury in mice
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Pharmaceutical Sciences"
DOI: 10.1016/j.ejps.2018.10.012
Abstract: Abstract An optimised 1,8‐cineole‐loaded self‐microemulsifying drug delivery system (CIN‐SMEDDS) with a mean droplet size, polydispersity index, mean zeta potential and encapsulation efficiency of 38.14 ± 1.47 nm, 0.208 ± 0.036, −9.312 ± 1.764 mV and… read more here.
Keywords: endothelial injury; induced endothelial; cin smedds; cineole loaded ... See more keywords
Exosomes derived from platelet-rich plasma mediate hyperglycemia-induced retinal endothelial injury via targeting the TLR4 signaling pathway.
Sign Up to like & getrecommendations! Published in 2019 at "Experimental eye research"
DOI: 10.1016/j.exer.2019.107813
Abstract: In this study, we aimed to investigate whether exosomes derived from platelet-rich plasma (PRP-Exos) can regulate hyperglycemia-induced retinal injury via targeting the TLR4 signaling pathway. We studied the effects of PRP-Exos on retinal endothelial injury… read more here.
Keywords: endothelial injury; induced retinal; prp exos; injury ... See more keywords
Non-targeted metabolomic analysis predicts the therapeutic effects of exenatide on endothelial injury in patients with type 2 diabetes.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of diabetes and its complications"
DOI: 10.1016/j.jdiacomp.2020.107797
Abstract: AIMS We aimed to investigate whether treatment with exenatide could ameliorate endothelial injury in patients with type 2 diabetes mellitus (T2DM), and to identify biomarkers for predicting amelioration of the endothelial injury induced by the… read more here.
Keywords: endothelial injury; injury patients; patients type; treatment ... See more keywords
Endothelial injury in COVID-19 and septic patients
Sign Up to like & getrecommendations! Published in 2021 at "Microvascular Research"
DOI: 10.1016/j.mvr.2021.104303
Abstract: Systemic inflammatory response, as observed in sepsis and severe COVID-19, may lead to endothelial damage. Therefore, we aim to compare the extent of endothelial injury and its relationship to inflammation in both diseases. We included… read more here.
Keywords: endothelial injury; group; injury; septic patients ... See more keywords
Vascular protective effects of aqueous extracts of Tribulus terrestris on hypertensive endothelial injury.
Sign Up to like & getrecommendations! Published in 2017 at "Chinese journal of natural medicines"
DOI: 10.1016/s1875-5364(17)30088-2
Abstract: Angiotensin II (Ang II) is involved in endothelium injury during the development of hypertension. Tribulus terrestris (TT) is used to treat hypertension, arteriosclerosis, and post-stroke syndrome in China. The present study aimed to determine the… read more here.
Keywords: endothelial injury; aqueous extracts; tribulus terrestris; effects aqueous ... See more keywords
Endoplasmic Reticulum Peroxynitrite Fluctuations in Hypoxia-Induced Endothelial Injury and Sepsis with a Two-Photon Fluorescence Probe.
Sign Up to like & getrecommendations! Published in 2023 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c05040
Abstract: Sepsis is a serious systemic inflammatory disease that frequently results in death. Early diagnosis and timely targeted interventions could improve the therapeutic effect. Recent work has revealed that the reactive oxygen species (ROS) in the… read more here.
Keywords: endothelial injury; endoplasmic reticulum; sepsis; hypoxia induced ... See more keywords
Effects of Intraoperative Support Strategies on Endothelial Injury and Clinical Lung Transplant Outcomes.
Sign Up to like & getrecommendations! Published in 2023 at "Seminars in thoracic and cardiovascular surgery"
DOI: 10.1053/j.semtcvs.2022.09.016
Abstract: In lung transplantation, postoperative outcomes favor intraoperative use of extracorporeal membrane oxygenation (ECMO) over cardiopulmonary bypass (CBP). We investigated the effect of intraoperative support strategies on endothelial injury biomarkers and short-term posttransplant outcomes. Adults undergoing… read more here.
Keywords: endothelial injury; lung transplantation; lung; support ... See more keywords
Berberine reduces endothelial injury and arterial stiffness in spontaneously hypertensive rats
Sign Up to like & getrecommendations! Published in 2019 at "Clinical and Experimental Hypertension"
DOI: 10.1080/10641963.2019.1632339
Abstract: ABSTRACT Background: Changes in circulating endothelial microparticles (EMPs) and endothelial progenitor cells (EPCs) are considered as a new perspective reflection of the endothelial injury and repair status. Our previous studies have demonstrated that berberine improved… read more here.
Keywords: endothelial injury; hypertensive rats; berberine; arterial stiffness ... See more keywords
Angiotensin-(1-7) ameliorates high glucose-induced vascular endothelial injury through suppressing chloride channel 3
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2021.1997695
Abstract: ABSTRACT Diabetes Mellitus (DM) is a significant risk factor for cardiovascular disease (CVD), which is leading cause of deaths in DM patients. However, there are limited effective medical therapies for diabetic CVD. Vascular endothelial injury… read more here.
Keywords: endothelial injury; diabetic cvd; injury; vascular endothelial ... See more keywords
Hypobaria Exposure Worsens Cardiac Function and Endothelial Injury in an Animal Model of Polytrauma: Implications for Aeromedical Evacuation.
Sign Up to like & getrecommendations! Published in 2020 at "Shock"
DOI: 10.1097/shk.0000000000001716
Abstract: BACKGROUND Aeromedical evacuation can expose traumatically injured patients to low pressure (hypobaria) and hypoxia. Here we sought to assess the impact of hypobaria on inflammation, organ injury, and mortality in a mouse model of polytrauma.… read more here.
Keywords: model polytrauma; hypobaria; endothelial injury; injury ... See more keywords
Bioinformatics-based analysis of mechanistic differences in vascular endothelial injury ischemic stroke induced by atrial fibrillation and atherosclerosis.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of neurochemistry"
DOI: 10.1111/jnc.15849
Abstract: Studies of the intracranial vasculature in patients with ischemic stroke caused by atherosclerosis (AS) and cardiac embolism have revealed significantly different degrees of AS, plaque, and vascular stenosis. And the endothelium has a great influence… read more here.
Keywords: endothelial injury; mechanistic differences; ischemic stroke; stroke ... See more keywords