MRI assessment of coronary microvascular endothelial nitric oxide synthase function using myocardial T1 mapping
Sign Up to like & getrecommendations! Published in 2018 at "Magnetic Resonance in Medicine"
DOI: 10.1002/mrm.26870
Abstract: Endothelial nitric oxide synthase (eNOS) plays a central role in regulating vascular tone, blood flow, and microvascular permeability. Endothelial dysfunction, including eNOS dysfunction, is an early biomarker of vascular disease. This study aimed to show… read more here.
Keywords: endothelial nitric; oxide synthase; nitric oxide; coronary microvascular ... See more keywords
Acute ischemic stroke induces magnetic resonance susceptibility signs dominated by endothelial nitric oxide synthase activation
Sign Up to like & getrecommendations! Published in 2020 at "Magnetic Resonance in Medicine"
DOI: 10.1002/mrm.28567
Abstract: Acute ischemic stroke induces deoxyhemoglobin accumulation around the ischemic region while activating endothelial nitric oxide synthase (eNOS) coupling and the subsequent release of nitric oxide (NO). Because deoxyhemoglobin is a natural NO spin trap, its… read more here.
Keywords: ischemic stroke; endothelial nitric; stroke induces; acute ischemic ... See more keywords
Endothelial nitric oxide synthase c.-813C>T predicts for proteinuria in metastatic breast cancer patients treated with bevacizumab-based chemotherapy
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Chemotherapy and Pharmacology"
DOI: 10.1007/s00280-019-03933-z
Abstract: To investigate the association between single nucleotide polymorphisms (SNPs) in endothelial nitric oxide synthase (eNOS) and interleukin-8 (IL-8) genes and risk of developing bevacizumab-related adverse events in metastatic breast cancer (mBC) patients. mBC patients candidate… read more here.
Keywords: bevacizumab based; endothelial nitric; nitric oxide; based chemotherapy ... See more keywords
Endothelial nitric oxide synthase oxygenase on lipid nanodiscs: A nano-assembly reflecting native-like function of eNOS.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.09.131
Abstract: Endothelial nitric oxide synthase (eNOS) is a membrane-anchored enzyme. To highlight the potential role and effect of membrane phospholipids on the structure and activity of eNOS, we have incorporated the recombinant oxygenase subunit of eNOS… read more here.
Keywords: endothelial nitric; oxygenase; lipid nanodiscs; oxide synthase ... See more keywords
Endothelial nitric oxide synthase plays a protective role against myocardial infarction
Sign Up to like & getrecommendations! Published in 2018 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2018.10.018
Abstract: Redox signaling has been implicated in the loss of proliferative/regenerative ability of cardiomyocytes (CMs) after birth. This is one of the main reasons why a mature, aged heart cannot regenerate following an extensive inschemic event,… read more here.
Keywords: endothelial nitric; myocardial infarction; cms; role ... See more keywords
Endothelial nitric oxide synthase gene polymorphisms and erectile dysfunction in chronic pain.
Sign Up to like & getrecommendations! Published in 2019 at "Gene"
DOI: 10.1016/j.gene.2019.100005
Abstract: OBJECTIVES To investigate whether endothelial nitric oxide synthase (eNOS) T786C, 4VNTR and G894 T gene polymorphisms could mediate in andrological treatment response in Spaniards. SUBJECT PATIENTS/METHODS The study participants were Spaniard males with erectile dysfunction (ED)… read more here.
Keywords: endothelial nitric; gene polymorphisms; oxide synthase; nitric oxide ... See more keywords
Chronic nitrite treatment activates adenosine monophosphate-activated protein kinase-endothelial nitric oxide synthase pathway in human aortic endothelial cells
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Functional Foods"
DOI: 10.1016/j.jff.2021.104447
Abstract: Abstract Endothelial dysfunction, with impaired bioavailability and/or bioactivity of the vasoprotective molecule, nitric oxide, appears to be a vital step in the initiation of atherosclerosis. Several studies have shown that dietary nitrate/nitrite can have significant… read more here.
Keywords: oxide synthase; nitric oxide; monophosphate activated; nitrate nitrite ... See more keywords
Endothelial dysfunction, endothelial nitric oxide bioavailability, tetrahydrobiopterin, and 5-methyltetrahydrofolate in cardiovascular disease. Where are we with therapy?
Sign Up to like & getrecommendations! Published in 2018 at "Microvascular research"
DOI: 10.1016/j.mvr.2018.03.012
Abstract: Homeostasis around vascular endothelium is a function of the equilibrium between the bioavailability of nitric oxide (NO) and oxidizing reactive oxygen species (ROS). Within the vascular endothelium, NO enhances vasodilatation, reduces platelet aggression and adhesion… read more here.
Keywords: nitric oxide; cardiovascular disease; endothelial dysfunction; endothelial nitric ... See more keywords
High glutathionylation of placental endothelial nitric oxide synthase in preeclampsia
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DOI: 10.1016/j.redox.2019.101126
Abstract: Decreased nitric oxide (NO) bioavailability plays a critical role in the pathophysiology of preeclampsia (PE). Recent evidence indicates that S-glutathionylation may occur on the endothelial nitric oxide synthase (eNOS), leading to eNOS uncoupling, characterized by… read more here.
Keywords: endothelial nitric; po2; glutathionylation; enos glutathionylation ... See more keywords
Contribution of glutaredoxin‐1 to S‐glutathionylation of endothelial nitric oxide synthase for mesenteric nitric oxide generation in experimental necrotizing enterocolitis
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DOI: 10.1016/j.trsl.2016.01.004
Abstract: &NA; Endothelial nitric oxide synthase (eNOS) is critical for intestinal microcirculatory perfusion and therefore plays a key role in the development of necrotizing enterocolitis (NEC). eNOS‐derived nitric oxide (NO) is inhibited by S‐glutathionylation of eNOS… read more here.
Keywords: enos ssg; endothelial nitric; necrotizing enterocolitis; oxide synthase ... See more keywords
Compensatory Vasodilator Mechanisms in the Ophthalmic Artery of Endothelial Nitric Oxide Synthase Gene Knockout Mice
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DOI: 10.1038/s41598-017-07768-7
Abstract: Nitric oxide (NO) generated by endothelial nitric oxide synthase (eNOS) plays an important role in the maintenance of ocular vascular homeostasis. Therefore, perturbations in vascular NO synthesis have been implicated in the pathogenesis of several… read more here.
Keywords: artery; endothelial nitric; ophthalmic artery; oxide synthase ... See more keywords