Impairing flow-mediated endothelial remodeling reduces extravasation of tumor cells
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-92515-2
Abstract: Tumor progression and metastatic dissemination are driven by cell-intrinsic and biomechanical cues that favor the growth of life-threatening secondary tumors. We recently identified pro-metastatic vascular regions with blood flow profiles that are permissive for the… read more here.
Keywords: blood flow; endothelial remodeling; tumor cells; extravasation ... See more keywords
Serial intravital imaging captures dynamic and functional endothelial remodeling with single-cell resolution
Sign Up to like & getrecommendations! Published in 2021 at "JCI Insight"
DOI: 10.1172/jci.insight.123392
Abstract: Endothelial cells are important in the maintenance of healthy blood vessels and in the development of vascular diseases. However, the origin and dynamics of endothelial precursors and remodeling at the single-cell level have been difficult… read more here.
Keywords: single cell; endothelial remodeling; remodeling single; endothelial cells ... See more keywords