Endothelial tight junctions and their regulatory signaling pathways in vascular homeostasis and disease.
Sign Up to like & getrecommendations! Published in 2019 at "Cellular signalling"
DOI: 10.1016/j.cellsig.2019.109485
Abstract: Endothelial tight junctions (TJs) regulate the transport of water, ions, and molecules through the paracellular pathway, serving as an important barrier in blood vessels and maintaining vascular homeostasis. In endothelial cells (ECs), TJs are highly… read more here.
Keywords: signaling pathways; endothelial tight; vascular homeostasis; tjs ... See more keywords
Manipulating ocular endothelial tight junctions: Applications in treatment of retinal disease pathology and ocular hypertension
Sign Up to like & getrecommendations! Published in 2018 at "Progress in Retinal and Eye Research"
DOI: 10.1016/j.preteyeres.2017.09.003
Abstract: Protein levels of endothelial tight-junctions of the inner retinal microvasculature, together with those of Schlemm's canal, can be readily manipulated by RNA interference (RNAi), resulting in the paracellular clefts between such cells to be reversibly… read more here.
Keywords: ocular endothelial; endothelial tight; junctions applications; pathology ... See more keywords
Targeting endothelial tight junctions to predict and protect thoracic aortic aneurysm and dissection.
Sign Up to like & getrecommendations! Published in 2023 at "European heart journal"
DOI: 10.1093/eurheartj/ehac823
Abstract: AIMS Whether changes in endothelial tight junctions (TJs) lead to the formation of thoracic aortic aneurysm and dissection (TAAD) and serve as an early indicator and therapeutic target remains elusive. METHODS AND RESULTS Single-cell RNA… read more here.
Keywords: aneurysm dissection; tight junctions; thoracic aortic; thoracic aortas ... See more keywords