An electrospun fiber-covered stent with programmable dual drug release for endothelialization acceleration and lumen stenosis prevention.
Sign Up to like & getrecommendations! Published in 2019 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2019.06.008
Abstract: Aneurysmal subarachnoid hemorrhage (SAH) causes high rates of mortality and morbidity. A covered stent is an effective endovascular treatment for complicated aneurysms intractable to endovascular coiling and surgical clipping. However, in-stent restenosis and delayed endothelialization… read more here.
Keywords: endothelialization; drug loaded; covered stent; drug ... See more keywords
Selection of different endothelialization modes and different seed cells for tissue-engineered vascular graft
Sign Up to like & getrecommendations! Published in 2021 at "Bioactive Materials"
DOI: 10.1016/j.bioactmat.2020.12.021
Abstract: Tissue-engineered vascular grafts (TEVGs) have enormous potential for vascular replacement therapy. However, thrombosis and intimal hyperplasia are important problems associated with TEVGs especially small diameter TEVGs ( read more here.
Keywords: endothelialization; seed; tissue engineered; seed cells ... See more keywords
Polyzwitterion-crosslinked hybrid tissue with antithrombogenicity, endothelialization, anticalcification properties
Sign Up to like & getrecommendations! Published in 2021 at "Chemical Engineering Journal"
DOI: 10.1016/j.cej.2020.128244
Abstract: Abstract Although transcatheter aortic valve implantation (TAVI) has been proven with excellent effectiveness and safety, the subclinical leaflet thrombosis (SLT) and structural valve deterioration (SVD) are two main factors threatening the service lifespan of the… read more here.
Keywords: endothelialization; porcine pericardium; anticalcification properties; tissue ... See more keywords
Mussel-inspired triblock functional protein coating with endothelial cell selectivity for endothelialization.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of colloid and interface science"
DOI: 10.1016/j.jcis.2020.04.116
Abstract: Surface modification of biomaterials for rapid endothelialization is a promising approach for improving long-term patency of artificial vascular grafts (e.g. polytetrafluoroethylene, PTFE) with small-caliber vascular ( read more here.
Keywords: protein; protein coating; endothelialization; triblock functional ... See more keywords
An inorganic coating and flexible regulating in situ of stent endothelialization by the controllable ion releasing
Sign Up to like & getrecommendations! Published in 2018 at "Materials Research Bulletin"
DOI: 10.1016/j.materresbull.2018.06.035
Abstract: Abstract A facile approach to fabricate an inorganic coating with favorable blood compatibility and accelerating endothelialization is reported. The inorganic coating with various ratios of Cu and Ti atom are prepared on 316 L stainless steel… read more here.
Keywords: inorganic coating; coating flexible; endothelialization; ion releasing ... See more keywords
A pre-conditioning protocol of peripheral blood derived endothelial colony forming cells for endothelialization of tissue engineered constructs.
Sign Up to like & getrecommendations! Published in 2020 at "Microvascular research"
DOI: 10.1016/j.mvr.2020.104107
Abstract: In regenerative medicine, autologous endothelial colony forming cells (ECFCs) bear the greatest potential to be used for surface endothelialization of tissue engineered constructs, as they are easily attainable and possess a high proliferation rate. The… read more here.
Keywords: endothelialization; colony forming; forming cells; tissue ... See more keywords
p38α in macrophages aggravates arterial endothelium injury by releasing IL-6 through phosphorylating megakaryocytic leukemia 1
Sign Up to like & getrecommendations! Published in 2020 at "Redox Biology"
DOI: 10.1016/j.redox.2020.101775
Abstract: Background Macrophages regulate the inflammatory response and affect re-endothelialization. Inflammation and macrophages play important roles in promoting tissue repair, but p38α mitogen-activated protein kinase's role in re-endothelialization is unknown. Methods and results Wire injuries of… read more here.
Keywords: endothelialization; megakaryocytic leukemia; p38 fllysmcre; p38 ... See more keywords
Endothelialization of titanium surfaces by bio-inspired cell adhesion peptide coatings.
Sign Up to like & getrecommendations! Published in 2019 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.9b00573
Abstract: Common interventional therapies for cardiovascular occlusive diseases, such as the implantation of stents, are at risk of complications like thrombosis or restenosis. Drug-eluting stents have improved patency but simultaneously worsen the endothelialization of the implant.… read more here.
Keywords: endothelialization; adhesion; titanium; titanium surfaces ... See more keywords
Rosuvastatin- and Heparin-Loaded Poly(l-lactide- co-caprolactone) Nanofiber Aneurysm Stent Promotes Endothelialization via Vascular Endothelial Growth Factor Type A Modulation.
Sign Up to like & getrecommendations! Published in 2018 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.8b11714
Abstract: This study explored a new rosuvastatin calcium- and heparin-loaded poly(l-lactide- co-caprolactone) (PLCL) scaffold for covered stents for treating aneurysms. The mechanism of rosuvastatin-induced endothelialization via vascular endothelial growth factor (VEGF)-A elevation was further explored. Rosu50,… read more here.
Keywords: endothelialization; heparin loaded; microscopy; rosuvastatin ... See more keywords
Sustained release of a synthetic structurally-tailored glycopolymer modulates endothelial cells for enhanced endothelialization of materials
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Materials Chemistry B"
DOI: 10.1039/c9tb00714h
Abstract: GAG-mimicking polymers were prepared by a novel method allowing close control of structure and can be used as potent synthetic bioactive modifiers to promote endothelialization of materials. read more here.
Keywords: structurally tailored; endothelialization materials; sustained release; endothelialization ... See more keywords
Application of Heparin/Collagen‐REDV Selective Active Interface on ePTFE Films to Enhance Endothelialization and Anticoagulation
Sign Up to like & getrecommendations! Published in 2018 at "Artificial Organs"
DOI: 10.1111/aor.13131
Abstract: Expanded polytetrafluoroethylene (ePTFE) prosthetic valves have been widely used in clinical applications in Asian countries. However, these valves still have limits with regard to thrombosis, neointimal hyperplasia, restenosis, and valvar vegetation. The achievement of in… read more here.
Keywords: endothelialization; redv; eptfe films; heparin collagen ... See more keywords