A Rapid In Vitro Endothelialization Approach for Small‐Diameter Vascular Grafts via Covalent Reaction
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202517779
Abstract: Small‐diameter vascular grafts are prone to thrombosis and stenosis mainly due to inadequate endothelialization. The current in vitro endothelial cells (ECs) seeding methods are time‐consuming and insufficient to resist blood flow erosion, which limited the… read more here.
Keywords: reaction; vascular grafts; grafts via; small diameter ... See more keywords
3D‐Printed Shape Memory Poly(alkylene terephthalate) Scaffolds as Cardiovascular Stents Revealing Enhanced Endothelialization
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202303498
Abstract: Cardiovascular diseases are the leading cause of death and current treatments such as stents still suffer from disadvantages. Balloon expansion causes damage to the arterial wall and limited and delayed endothelialization gives rise to restenosis… read more here.
Keywords: cardiovascular stents; shape memory; terephthalate; poly ... See more keywords
Plasma-Polymerized Nanoparticles Presenting Fibrillin-1 Drive Rapid Re-Endothelialization of Vascular Grafts.
Sign Up to like & getrecommendations! Published in 2025 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202503360
Abstract: Small diameter vascular grafts made from expanded polytetrafluoroethylene (ePTFE) dominate clinical practice but are prone to high failure rates due to poor endothelialization, acute thrombosis or mid-term neointimal hyperplasia. The highly hydrophobic surface of ePTFE… read more here.
Keywords: plasma polymerized; vascular grafts; polymerized nanoparticles; nanoparticles presenting ... See more keywords
An electrospun fiber-covered stent with programmable dual drug release for endothelialization acceleration and lumen stenosis prevention.
Sign Up to like & getrecommendations! Published in 2019 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2019.06.008
Abstract: Aneurysmal subarachnoid hemorrhage (SAH) causes high rates of mortality and morbidity. A covered stent is an effective endovascular treatment for complicated aneurysms intractable to endovascular coiling and surgical clipping. However, in-stent restenosis and delayed endothelialization… read more here.
Keywords: endothelialization; drug loaded; covered stent; drug ... See more keywords
Selection of different endothelialization modes and different seed cells for tissue-engineered vascular graft
Sign Up to like & getrecommendations! Published in 2021 at "Bioactive Materials"
DOI: 10.1016/j.bioactmat.2020.12.021
Abstract: Tissue-engineered vascular grafts (TEVGs) have enormous potential for vascular replacement therapy. However, thrombosis and intimal hyperplasia are important problems associated with TEVGs especially small diameter TEVGs ( read more here.
Keywords: endothelialization; seed; tissue engineered; seed cells ... See more keywords
Polyzwitterion-crosslinked hybrid tissue with antithrombogenicity, endothelialization, anticalcification properties
Sign Up to like & getrecommendations! Published in 2021 at "Chemical Engineering Journal"
DOI: 10.1016/j.cej.2020.128244
Abstract: Abstract Although transcatheter aortic valve implantation (TAVI) has been proven with excellent effectiveness and safety, the subclinical leaflet thrombosis (SLT) and structural valve deterioration (SVD) are two main factors threatening the service lifespan of the… read more here.
Keywords: endothelialization; porcine pericardium; anticalcification properties; tissue ... See more keywords
Mussel-inspired triblock functional protein coating with endothelial cell selectivity for endothelialization.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of colloid and interface science"
DOI: 10.1016/j.jcis.2020.04.116
Abstract: Surface modification of biomaterials for rapid endothelialization is a promising approach for improving long-term patency of artificial vascular grafts (e.g. polytetrafluoroethylene, PTFE) with small-caliber vascular ( read more here.
Keywords: protein; protein coating; endothelialization; triblock functional ... See more keywords
An inorganic coating and flexible regulating in situ of stent endothelialization by the controllable ion releasing
Sign Up to like & getrecommendations! Published in 2018 at "Materials Research Bulletin"
DOI: 10.1016/j.materresbull.2018.06.035
Abstract: Abstract A facile approach to fabricate an inorganic coating with favorable blood compatibility and accelerating endothelialization is reported. The inorganic coating with various ratios of Cu and Ti atom are prepared on 316 L stainless steel… read more here.
Keywords: inorganic coating; coating flexible; endothelialization; ion releasing ... See more keywords
A pre-conditioning protocol of peripheral blood derived endothelial colony forming cells for endothelialization of tissue engineered constructs.
Sign Up to like & getrecommendations! Published in 2020 at "Microvascular research"
DOI: 10.1016/j.mvr.2020.104107
Abstract: In regenerative medicine, autologous endothelial colony forming cells (ECFCs) bear the greatest potential to be used for surface endothelialization of tissue engineered constructs, as they are easily attainable and possess a high proliferation rate. The… read more here.
Keywords: endothelialization; colony forming; forming cells; tissue ... See more keywords
p38α in macrophages aggravates arterial endothelium injury by releasing IL-6 through phosphorylating megakaryocytic leukemia 1
Sign Up to like & getrecommendations! Published in 2020 at "Redox Biology"
DOI: 10.1016/j.redox.2020.101775
Abstract: Background Macrophages regulate the inflammatory response and affect re-endothelialization. Inflammation and macrophages play important roles in promoting tissue repair, but p38α mitogen-activated protein kinase's role in re-endothelialization is unknown. Methods and results Wire injuries of… read more here.
Keywords: endothelialization; megakaryocytic leukemia; p38 fllysmcre; p38 ... See more keywords
Endothelialization of titanium surfaces by bio-inspired cell adhesion peptide coatings.
Sign Up to like & getrecommendations! Published in 2019 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.9b00573
Abstract: Common interventional therapies for cardiovascular occlusive diseases, such as the implantation of stents, are at risk of complications like thrombosis or restenosis. Drug-eluting stents have improved patency but simultaneously worsen the endothelialization of the implant.… read more here.
Keywords: endothelialization; adhesion; titanium; titanium surfaces ... See more keywords