Crosstalk between the angiotensin and endothelin system in the cerebrovasculature after experimental induced subarachnoid hemorrhage
Sign Up to like & getrecommendations! Published in 2017 at "Neurosurgical Review"
DOI: 10.1007/s10143-017-0887-z
Abstract: Under physiologic conditions, losartan showed a dose-dependent antagonistic effect to the endothelin-1 (ET-1)-mediated vasoconstriction. This reduced vasoconstriction was abolished after preincubation with an endothelin B1 receptor (ET(B1)-receptor) antagonist. Also, an increased ET(B1)-receptor-dependent relaxation to sarafotoxin… read more here.
Keywords: induced subarachnoid; subarachnoid hemorrhage; experimental induced; endothelin ... See more keywords
The endothelin 1 and endothelin receptor A gene polymorphisms increase the risk of developing papillary thyroid cancer
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Biology Reports"
DOI: 10.1007/s11033-018-4461-8
Abstract: The endothelin (EDN) axis (EDN1 and EDN1 receptor A, EDNRA) is involved in cellular growth, differentiation, invasiveness, and tumor progression in several cancers. We wanted to examine the possible impact of single nucleotide polymorphisms (SNPs)… read more here.
Keywords: risk; edn1; papillary thyroid; snp ... See more keywords
The relation of RAAS activity and endothelin-1 levels to coronary atherosclerotic burden and microvascular dysfunction in chest pain patients.
Sign Up to like & getrecommendations! Published in 2022 at "Atherosclerosis"
DOI: 10.1016/j.atherosclerosis.2022.03.017
Abstract: BACKGROUND AND AIMS In this study, we investigated whether increased renin angiotensin aldosterone system (RAAS) activation and endothelin-1 levels are related to coronary artery calcium (CAC) score, total plaque volume (TPV), high risk plaque, hyperemic… read more here.
Keywords: raas; renin; microvascular dysfunction; cad ... See more keywords
Deletion of the myeloid endothelin-B receptor confers long-term protection from angiotensin II-mediated kidney, eye and vessel injury
Sign Up to like & getrecommendations! Published in 2020 at "Kidney International"
DOI: 10.1016/j.kint.2020.05.042
Abstract: The endothelin system may be an important player in hypertensive end-organ injury as endothelin-1 increases blood pressure and is pro-inflammatory. The immune system is emerging as an important regulator of blood pressure and we have… read more here.
Keywords: lox mice; endothelin; lysm creednrblox; creednrblox lox ... See more keywords
Interactions between the complement and endothelin systems in normal pregnancy and following placental ischemia.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular immunology"
DOI: 10.1016/j.molimm.2019.06.015
Abstract: Preeclampsia is characterized by new onset hypertension and fetal growth restriction and is associated with aberrant activation of the innate immune complement system and stressed or ischemic placenta. Previous studies have suggested a role for… read more here.
Keywords: placental ischemia; pregnancy; complement; activation ... See more keywords
Predictive role of endothelin in left ventricular remodeling of chronic kidney disease
Sign Up to like & getrecommendations! Published in 2018 at "Renal Failure"
DOI: 10.1080/0886022x.2018.1455586
Abstract: Abstract Background: In chronic kidney disease (CKD), endothelin-1 (ET-1) always increases and there are changes in cardiac ultrasonography. In the present study, we aimed at investigating the role of serum ET-1 in predicting cardiac complications… read more here.
Keywords: endothelin; kidney disease; left ventricular; chronic kidney ... See more keywords
A novel role for myeloid endothelin-B receptors in hypertension
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DOI: 10.1093/eurheartj/ehy881
Abstract: Abstract Aims Hypertension is common. Recent data suggest that macrophages (Mφ) contribute to, and protect from, hypertension. Endothelin-1 (ET-1) is the most potent endogenous vasoconstrictor with additional pro-inflammatory properties. We investigated the role of the… read more here.
Keywords: role myeloid; novel role; role; hypertension ... See more keywords
Endothelial dysfunction and features of nociceptive sensitivity in patients with microvascular angina
Sign Up to like & getrecommendations! Published in 2021 at "European Journal of Preventive Cardiology"
DOI: 10.1093/eurjpc/zwab061.059
Abstract: Type of funding sources: Public Institution(s). Main funding source(s): фГБ ОУ ВО СЗГМУ им. И.И. Мечникова Introduction. The pathogenesis of microvascular angina pectoris (MVA) is not completely clear to the end, some authors consider the… read more here.
Keywords: pain; nociceptive sensitivity; patients mva; pain threshold ... See more keywords
Physiological role of endothelin-1 in flow-mediated vasodilatation in humans and impact of cardiovascular risk factors
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DOI: 10.1097/hjh.0000000000001307
Abstract: Objectives: The current study addressed the hypothesis that the local decrease in endothelin-1 (ET-1) bioavailability during sustained flow increases contributes to endothelium-dependent, flow-mediated dilatation (FMD) of conduit arteries and is altered in presence of cardiovascular… read more here.
Keywords: flow mediated; cardiovascular risk; risk factors; endothelin ... See more keywords
Endothelin‐1 and its receptors on haemorrhoidal tissue: a potential site for therapeutic intervention
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DOI: 10.1111/bph.13719
Abstract: Haemorrhoids is a common anorectal condition affecting millions worldwide. We have studied the effect of endothelin‐1 (ET‐1) and the role of endothelin ETA and ETB receptors in haemorrhoid tissue. read more here.
Keywords: receptors haemorrhoidal; haemorrhoidal tissue; tissue potential; endothelin receptors ... See more keywords
Investigating the level of salivary endothelin‐1 in premalignant and malignant lesions
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DOI: 10.1111/scd.12217
Abstract: PURPOSE This study aimed to investigate the level of salivary endothelin-1 in premalignant and malignant lesions. MATERIALS AND METHODS In this study, 75 cases were investigated of which 25 cases were healthy, 25 cases had… read more here.
Keywords: malignant lesions; salivary endothelin; premalignant malignant; level salivary ... See more keywords