Aprocitentan and the endothelin system in resistant hypertension.
Sign Up to like & getrecommendations! Published in 2022 at "Canadian journal of physiology and pharmacology"
DOI: 10.1139/cjpp-2022-0010
Abstract: Endothelin has emerged as a target for therapeutic intervention in systemic hypertension. As a vasoconstrictor, co-mitogenic agent, linking pulse pressure and vascular remodeling, and mediator of aldosterone and catecholamine release, endothelin is a key player… read more here.
Keywords: endothelin system; hypertension; endothelin; antihypertensive drugs ... See more keywords
Endothelin System and Ischemia-Induced Ventricular Tachyarrhythmias
Sign Up to like & getrecommendations! Published in 2022 at "Life"
DOI: 10.3390/life12101627
Abstract: Despite the contemporary treatment of acute coronary syndromes, arrhythmic complications occurring prior to medical attendance remain significant, mandating in-depth understanding of the underlying mechanisms. Sympathetic activation has long been known to play a key role… read more here.
Keywords: system; endothelin system; ischemia induced; induced ventricular ... See more keywords