High‐Throughput Screening of Vascular Endothelium‐Destructive or Protective Microenvironments: Cooperative Actions of Extracellular Matrix Composition, Stiffness, and Structure
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DOI: 10.1002/adhm.201601426
Abstract: Pathological modification of the subendothelial extracellular matrix (ECM) has closely been associated with endothelial activation and subsequent cardiovascular disease progression. To understand regulatory mechanisms of these matrix modifications, the majority of previous efforts have focused… read more here.
Keywords: endothelium; extracellular matrix; stiffness structure; composition ... See more keywords
Coaxial Cell Printing of Freestanding, Perfusable, and Functional In Vitro Vascular Models for Recapitulation of Native Vascular Endothelium Pathophysiology
Sign Up to like & getrecommendations! Published in 2018 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.201801102
Abstract: 3D printing technology is used to produce channels within hydrogels followed by endothelial cells (ECs)-seeding to establish in vitro vascular models. However, as built-in bulk hydrogels, it is difficult to incorporate additional cells and molecules… read more here.
Keywords: vitro vascular; endothelium; coaxial cell; cell printing ... See more keywords
Endothelial Cells and the Cerebral Circulation.
Sign Up to like & getrecommendations! Published in 2022 at "Comprehensive Physiology"
DOI: 10.1002/cphy.c210015
Abstract: Endothelial cells form the innermost layer of all blood vessels and are the only vascular component that remains throughout all vascular segments. The cerebral vasculature has several unique properties not found in the peripheral circulation;… read more here.
Keywords: endothelium; endothelial cells; brain; physiology ... See more keywords
Tissue Specificity: SOCE: Implications for Ca2+ Handling in Endothelial Cells.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-319-57732-6_18
Abstract: Many cellular functions of the vascular endothelium are regulated by fine-tuned global and local, microdomain-confined changes of cytosolic free Ca2+ ([Ca2+]i). Vasoactive agonist-induced stimulation of vascular endothelial cells (VECs) typically induces Ca2+ release through IP3… read more here.
Keywords: endothelium; vascular endothelial; ca2 release; endothelial cells ... See more keywords
Human endoglin as a potential new partner involved in platelet–endothelium interactions
Sign Up to like & getrecommendations! Published in 2017 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-017-2694-7
Abstract: Complex interactions between platelets and activated endothelium occur during the thrombo-inflammatory reaction at sites of vascular injuries and during vascular hemostasis. The endothelial receptor endoglin is involved in inflammation through integrin-mediated leukocyte adhesion and transmigration;… read more here.
Keywords: endothelium; human endoglin; adhesion; endothelial cells ... See more keywords
Endothelium-dependent vasodilation in the cerebral arterioles of rats deteriorates during acute hyperglycemia and then is restored by reducing the glucose level
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Anesthesia"
DOI: 10.1007/s00540-018-2507-7
Abstract: PurposeAcute hyperglycemia in patients with traumatic brain injury correlates with a poor neurological outcome. We investigated the endothelium function of rat cerebral arterioles during acute hyperglycemia and after reducing the glucose levels using insulin. We… read more here.
Keywords: endothelium; reducing glucose; cerebral arterioles; hyperglycemia ... See more keywords
ADAM10 controls the differentiation of the coronary arterial endothelium
Sign Up to like & getrecommendations! Published in 2018 at "Angiogenesis"
DOI: 10.1007/s10456-018-9653-2
Abstract: The coronary vasculature is crucial for normal heart function, yet much remains to be learned about its development, especially the maturation of coronary arterial endothelium. Here, we show that endothelial inactivation of ADAM10, a key… read more here.
Keywords: adam10; endothelium; arterial endothelium; coronary arterial ... See more keywords
Fate of endothelial cells after intrastromal implantation of Descemet’s membrane-endothelial cell tissue
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DOI: 10.1007/s10561-020-09840-5
Abstract: In non-Descemet Stripping Automated Endothelial Keratoplasty (nDSAEK), the host DM and endothelium are not removed surgically before the introduction of the posterior lamellar graft; the result is that the patient has both the healthy donor… read more here.
Keywords: endothelium; stromal pocket; endothelial cell; endothelial cells ... See more keywords
In Vivo Molecular MRI of ICAM-1 Expression on Endothelium and Leukocytes from Subacute to Chronic Stages After Experimental Stroke
Sign Up to like & getrecommendations! Published in 2017 at "Translational Stroke Research"
DOI: 10.1007/s12975-017-0536-4
Abstract: Molecular MRI allows in vivo detection of vascular cell adhesion molecules expressed on inflamed endothelium, which enables detection of specific targets for anti-neuroinflammatory treatment. We explored to what extent MR contrast agent targeted to intercellular… read more here.
Keywords: icam expression; endothelium; icam mpio; icam ... See more keywords
Revealing anisotropic elasticity of endothelium under fluid shear stress.
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DOI: 10.1016/j.actbio.2022.03.040
Abstract: Endothelium lining interior surface of blood vessels experiences various physical stimulations in vivo. Its physical properties, especially elasticity, play important roles in regulating the physiological functions of vascular systems. In this paper, an integrated approach… read more here.
Keywords: fluid shear; endothelium; direction; shear stress ... See more keywords
Corneal Endothelium:A Promising Quantitative Index for Graves Ophthalmopathy Activity Evaluation.
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DOI: 10.1016/j.ajo.2021.05.020
Abstract: PURPOSE To investigate the corneal endothelium damage in Graves ophthalmopathy (GO) and its role as a promising quantitative index to evaluate GO activity. DESIGN Cross-sectional study. METHODS This study included 128 eyes of 64 patients… read more here.
Keywords: corneal endothelium; activity; endothelium; quantitative index ... See more keywords