Endotoxin contamination of engineered nanomaterials: Overcoming the hurdles associated with endotoxin testing.
Sign Up to like & getrecommendations! Published in 2021 at "Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology"
DOI: 10.1002/wnan.1738
Abstract: Nanomaterials are highly susceptible to endotoxin contamination due their large surface-to-volume ratios and endotoxins propensity to associate readily to hydrophobic and cationic surfaces. Additionally, the stability of endotoxin ensures it cannot be removed efficiently through… read more here.
Keywords: engineered nanomaterials; endotoxin contamination; endotoxin; contamination engineered ... See more keywords
Interlaboratory comparison of endotoxin contamination assessment of nanomaterials.
Sign Up to like & getrecommendations! Published in 2024 at "Nanoscale"
DOI: 10.1039/d4nr02821j
Abstract: Endotoxin contamination is a significant hurdle to the translation of nanomaterials for biomedical applications. Multiple reports now describe that more than one-third of nanomaterials fail early pre-clinical assessment due to levels of endotoxin above regulatory… read more here.
Keywords: contamination assessment; interlaboratory comparison; endotoxin contamination; assessment ... See more keywords
Endotoxin Contamination in Nanomaterials Leads to the Misinterpretation of Immunosafety Results
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2017.00472
Abstract: Given the presence of engineered nanomaterials in consumers’ products and their application in nanomedicine, nanosafety assessment is becoming increasingly important. In particular, immunosafety aspects are being actively investigated. In nanomaterial immunosafety testing strategies, it is… read more here.
Keywords: leads misinterpretation; endotoxin contamination; endotoxin; immunosafety ... See more keywords