Endotoxin contamination of engineered nanomaterials: Overcoming the hurdles associated with endotoxin testing.
Sign Up to like & getrecommendations! Published in 2021 at "Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology"
DOI: 10.1002/wnan.1738
Abstract: Nanomaterials are highly susceptible to endotoxin contamination due their large surface-to-volume ratios and endotoxins propensity to associate readily to hydrophobic and cationic surfaces. Additionally, the stability of endotoxin ensures it cannot be removed efficiently through… read more here.
Keywords: engineered nanomaterials; endotoxin contamination; endotoxin; contamination engineered ... See more keywords
Miniaturization, Parallelization, and Automation of Endotoxin Detection by Centrifugal Microfluidics.
Sign Up to like & getrecommendations! Published in 2021 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.1c01041
Abstract: We demonstrate microfluidic automation and parallelization of Limulus amebocyte lysate (LAL)-based bacterial endotoxin testing using centrifugal microfluidics. LAL is the standard reagent to test for endotoxin contaminations in injectable pharmaceuticals. The main features of the… read more here.
Keywords: miniaturization parallelization; endotoxin; centrifugal microfluidics; automation ... See more keywords