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   Articles with "endotype" as a keyword



Identification of Inflammatory Endotypes by Clinical Characteristics and Nasal Secretion Biomarkers in Chronic Rhinosinusitis with Nasal Polyps.

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recommendations! Published in 2023 at "International archives of allergy and immunology"

DOI: 10.1159/000530193

Abstract: INTRODUCTION The emergency of biologics and surgical techniques targeting the specific inflammatory endotype in chronic rhinosinusitis with nasal polyps (CRSwNP) asks for efficient identification of patients with different endotypes. Although mucosal IL-4, IL-5, IL-13, and… read more here.

Keywords: nasal secretion; characteristics nasal; secretion biomarkers; secretion ... See more keywords

Endotoxin: a bona fide treatable sepsis endotype?

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recommendations! Published in 2025 at "Blood purification"

DOI: 10.1159/000546294

Abstract: BACKGROUND The recognition of syndromes has been a pillar of medical education and knowledge. However, treatment of syndromes is challenging because there is a disconnect between the underlying mechanisms that lead to organ injury and… read more here.

Keywords: endotype; endotoxin; bona fide; sepsis ... See more keywords

Deep learning in computed tomography to predict endotype in chronic rhinosinusitis with nasal polyps

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recommendations! Published in 2024 at "BMC Medical Imaging"

DOI: 10.1186/s12880-024-01203-w

Abstract: Background As treatment strategies differ according to endotype, rhinologists must accurately determine the endotype in patients affected by chronic rhinosinusitis with nasal polyps (CRSwNP) for the appropriate management. In this study, we aim to construct… read more here.

Keywords: deep learning; learning model; endotype; predict endotype ... See more keywords

Molecular endotypes in sepsis: integration of multicohort transcriptomics based on RNA sequencing

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recommendations! Published in 2025 at "Journal of Intensive Care"

DOI: 10.1186/s40560-025-00802-1

Abstract: The heterogeneity of host responses in sepsis has hindered efforts to develop targeted therapies for this large patient population. Although growing evidence has identified sepsis endotypes based on the microarray data, studies using RNA-seq data—which… read more here.

Keywords: adaptive endotype; endotype; rna seq; molecular endotypes ... See more keywords