1,1-Carboamination of Terminal Alkenes via a Reaction of Azo-Ene Adducts with Grignard Reagents.
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DOI: 10.1021/acs.orglett.2c02585
Abstract: Facile conversion of petrochemical feedstocks into valuable amine molecules remains a long-standing challenge in organic chemistry. Here, we report a modular and practical alkene 1,1-carboamination technology that relies on sequential azo-ene reactions and attendant base-promoted… read more here.
Keywords: terminal alkenes; grignard reagents; adducts grignard; ene adducts ... See more keywords