Feeling Exhausted? Tuning Irf4 Energizes Dysfunctional T Cells.
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DOI: 10.1016/j.immuni.2017.11.028
Abstract: The regulatory mechanisms governing T cell exhaustion remain incompletely understood. Man et al. (2017) and Wu et al. (2017) report that the T cell receptor responsive transcription factor Irf4 promotes T cell exhaustion in chronic viral infection but dampens exhaustion… read more here.
Keywords: feeling exhausted; exhausted tuning; energizes dysfunctional; irf4 energizes ... See more keywords