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Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c03172
Abstract: Higher-energy collisional dissociation (HCD) of modified ribonucleosides generates characteristic and highly reproducible nucleoside-specific tandem mass spectra (MS/MS). Here, we demonstrate the capability of HCD spectra in combination with spectral matching for the semi-automated characterization of…
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Keywords:
collisional dissociation;
energy collisional;
semi automated;
higher energy ... See more keywords
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Published in 2020 at "Journal of the American Society for Mass Spectrometry"
DOI: 10.1021/jasms.9b00089
Abstract: With the optional setting of multiple stepped collisional energies (NCEs), higher-energy collisional dissociation (HCD) as available on Orbitrap instruments is a widely adopted dissociation method for intact N-glycopeptide characterization, where peptide backbones and N-glycan moieties…
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Keywords:
energy;
dissociation;
collisional dissociation;
energy collisional ... See more keywords