Metformin selectively targets redox control of complex I energy transduction
Sign Up to like & getrecommendations! Published in 2018 at "Redox Biology"
DOI: 10.1016/j.redox.2017.08.018
Abstract: Many guanide-containing drugs are antihyperglycaemic but most exhibit toxicity, to the extent that only the biguanide metformin has enjoyed sustained clinical use. Here, we have isolated unique mitochondrial redox control properties of metformin that are… read more here.
Keywords: metformin selectively; redox control; energy transduction;
Theory of Nonequilibrium Free Energy Transduction by Molecular Machines.
Sign Up to like & getrecommendations! Published in 2019 at "Chemical reviews"
DOI: 10.1021/acs.chemrev.9b00254
Abstract: Biomolecular machines are protein complexes that convert between different forms of free energy. They are utilized in nature to accomplish many cellular tasks. As isothermal nonequilibrium stochastic objects at low Reynolds number, they face a… read more here.
Keywords: energy; theory nonequilibrium; energy transduction; transduction molecular ... See more keywords
High-performance nanoscale topological energy transduction
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-06965-8
Abstract: The realization of high-performance, small-footprint, on-chip inductors remains a challenge in radio-frequency and power microelectronics, where they perform vital energy transduction in filters and power converters. Modern planar inductors consist of metallic spirals that consume… read more here.
Keywords: high performance; performance nanoscale; energy transduction; energy ... See more keywords