Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome
Sign Up to like & getrecommendations! Published in 2018 at "Nature"
DOI: 10.1038/s41586-018-0736-4
Abstract: The proteasome is an ATP-dependent, 2.5-megadalton molecular machine that is responsible for selective protein degradation in eukaryotic cells. Here we present cryo-electron microscopy structures of the substrate-engaged human proteasome in seven conformational states at 2.8–3.6 Å… read more here.
Keywords: engaged human; microscopy; substrate engaged; structures dynamics ... See more keywords