Balanced engagement of activating and inhibitory receptors mitigates human NK cell exhaustion
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DOI: 10.1172/jci.insight.150079
Abstract: NK cell exhaustion is caused by chronic exposure to activating stimuli during viral infection, tumorigenesis, and prolonged cytokine treatment. Evidence suggests that exhaustion may play a role in disease progression. However, relative to T cell… read more here.
Keywords: cell; balanced engagement; exhaustion; engagement activating ... See more keywords