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Published in 2017 at "British journal of clinical pharmacology"
DOI: 10.1111/bcp.13143
Abstract: AIM To develop a non-invasive, safe and reproducible target-engagement biomarker for future TRPA1 antagonists in healthy volunteers. METHODS Dose finding (n = 11): 3%, 10%, and 30% cinnamaldehyde (CA) and placebo (= vehicle) was topically applied on…
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Keywords:
min;
target engagement;
engagement biomarker;
trpa1 antagonists ... See more keywords