T cell engagers in solid tumors kick the door down.
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DOI: 10.1016/j.ccell.2021.10.005
Abstract: Tebentafusp, a T cell-redirecting, bispecific-antibody-targeting, HLA∗02:01-restricted gp100 peptide and CD3, induces T cells to kill glycoprotein 100 (gp100)-expressing tumor cells. Tebentafusp is the first T cell engager to show a statistically significant overall survival improvement for the treatment… read more here.
Keywords: engagers solid; solid tumors; cell engagers; tumors kick ... See more keywords