Articles with "engineered ancestral" as a keyword



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Efficient Base-Catalyzed Kemp Elimination in an Engineered Ancestral Enzyme

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms23168934

Abstract: The routine generation of enzymes with completely new active sites is one of the major unsolved problems in protein engineering. Advances in this field have been so far modest, perhaps due, at least in part,… read more here.

Keywords: efficient base; kemp elimination; engineering; elimination ... See more keywords