Synergistic Brilliance: Engineered Bacteria and Nanomedicine Unite in Cancer Therapy
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Materials"
DOI: 10.1002/adma.202313953
Abstract: Engineered bacteria are widely used in cancer treatment because live facultative/obligate anaerobes can selectively proliferate at tumor sites and reach hypoxic regions, thereby causing nutritional competition, enhancing immune responses, and producing anticancer microbial agents in… read more here.
Keywords: cancer; engineered bacteria; synergistic brilliance; cancer therapy ... See more keywords
Physiochemically and Genetically Engineered Bacteria: Instructive Design Principles and Diverse Applications
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Science"
DOI: 10.1002/advs.202403156
Abstract: With the comprehensive understanding of microorganisms and the rapid advances of physiochemical engineering and bioengineering technologies, scientists are advancing rationallyâengineered bacteria as emerging drugs for treating various diseases in clinical disease management. Engineered bacteria specifically… read more here.
Keywords: design principles; engineered bacteria; genetically engineered; physiochemically genetically ... See more keywords
Genetically Engineered Bacteria as a Promising Therapeutic Strategy Against Cancer: A Comprehensive Review
Sign Up to like & getrecommendations! Published in 2025 at "Biotechnology and Applied Biochemistry"
DOI: 10.1002/bab.2738
Abstract: As a significant cause of global mortality, the cancer has also economic impacts. In the era of cancer therapy, mitigating side effects and costs and overcoming drug resistance is crucial. Microbial species can grow inside… read more here.
Keywords: cancer; engineered bacteria; bacteria promising; genetically engineered ... See more keywords
Dietary Fatty Acids Control the Species of N-Acyl-Phosphatidylethanolamines Synthesized by Therapeutically Modified Bacteria in the Intestinal Tract.
Sign Up to like & getrecommendations! Published in 2018 at "ACS infectious diseases"
DOI: 10.1021/acsinfecdis.7b00127
Abstract: Engineering the gut microbiota to produce specific beneficial metabolites represents an important new potential strategy for treating chronic diseases. Our previous studies with bacteria engineered to produce N-acyl-phosphatidylethanolamines (NAPEs), the immediate precursors of the lipid… read more here.
Keywords: dietary fatty; acyl phosphatidylethanolamines; fatty acids; acids control ... See more keywords
Precise Thermal Regulation of Engineered Bacteria Secretion for Breast Cancer Treatment In Vivo.
Sign Up to like & getrecommendations! Published in 2022 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.1c00452
Abstract: For the biomedical application of engineered bacteria, strictly regulating the function of engineered bacteria has always been the goal pursued. However, the existing regulation methods do not meet the needs of the in vivo application… read more here.
Keywords: engineered bacteria; precise thermal; regulation engineered; thermal regulation ... See more keywords
Hyperbaric oxygen enhances tumor penetration and accumulation of engineered bacteria for synergistic photothermal immunotherapy
Sign Up to like & getrecommendations! Published in 2024 at "Nature Communications"
DOI: 10.1038/s41467-024-49156-6
Abstract: Bacteria-mediated cancer therapeutic strategies have attracted increasing interest due to their intrinsic tumor tropism. However, bacteria-based drugs face several challenges including the large size of bacteria and dense extracellular matrix, limiting their intratumoral delivery efficiency.… read more here.
Keywords: engineered bacteria; therapy; accumulation; tumor ... See more keywords
Engineered bacteria for augmented in situ tumor vaccination.
Sign Up to like & getrecommendations! Published in 2023 at "Biomaterials science"
DOI: 10.1039/d2bm01593e
Abstract: In situ tumor vaccination has aroused tremendous interest with its capability for eliciting strong and systemic antitumor immune responses. Unlike traditional cancer vaccines, in situ tumor vaccination avoids the laborious process of tumor antigen identification… read more here.
Keywords: bacteria augmented; vaccination; tumor vaccination; engineered bacteria ... See more keywords
Engineered bacteria for cancer therapy: Advancements, challenges, and future directions.
Sign Up to like & getrecommendations! Published in 2025 at "Chinese medical journal"
DOI: 10.1097/cm9.0000000000003807
Abstract: Abstract Recent advancements in cancer therapeutics, including targeted therapies and immunotherapies, have significantly improved treatment outcomes but remain limited by challenges such as off-target toxicity, poor penetration into deep tumor tissues, and the emergence of… read more here.
Keywords: cancer; bacteria cancer; therapy advancements; engineered bacteria ... See more keywords
A Multiscale Communications System Based on Engineered Bacteria
Sign Up to like & getrecommendations! Published in 2021 at "IEEE Communications Magazine"
DOI: 10.1109/mcom.001.2000964
Abstract: Although molecular communication systems have been shown to bear great potential for many useful in-body applications, they require the intervention, action, or input of an out-of-body actor. From an Internet of Bio-Nano Things perspective, a… read more here.
Keywords: system; body; multiscale communications; communications system ... See more keywords
Computational Models for Trapping Ebola Virus Using Engineered Bacteria
Sign Up to like & getrecommendations! Published in 2018 at "IEEE/ACM Transactions on Computational Biology and Bioinformatics"
DOI: 10.1109/tcbb.2018.2836430
Abstract: The outbreak of the Ebola virus in recent years has resulted in numerous research initiatives to seek new solutions to contain the virus. A number of approaches that have been investigated include new vaccines to… read more here.
Keywords: ebola virus; trapping ebola; models trapping; computational models ... See more keywords
Sustainable therapies by engineered bacteria
Sign Up to like & getrecommendations! Published in 2017 at "Microbial Biotechnology"
DOI: 10.1111/1751-7915.12778
Abstract: The controlled in situ delivery of biologics (e.g. enzymes, cytokines, antibodies) by engineered bacteria of our microbiome will allow the sustainable production of these complex and expensive drugs locally in the human body, overcoming many… read more here.
Keywords: sustainable therapies; engineered bacteria; therapies engineered;