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Published in 2020 at "Advanced materials"
DOI: 10.1002/adma.202001808
Abstract: The recent success of immunotherapies has highlighted the power of leveraging the immune system in the fight against cancer. In order for most immune-based therapies to succeed, T cell subsets with the correct tumor-targeting specificities…
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Keywords:
cell membrane;
antigen;
engineered cell;
cell ... See more keywords
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Published in 2023 at "Small Methods"
DOI: 10.1002/smtd.202200925
Abstract: Immune intervention of B cell activation to blockade the production of autoantibodies provokes intense interest in the field of systemic lupus erythematosus (SLE) therapy development. Although the survival rate for SLE is improved, many patients…
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Keywords:
engineered cell;
cell;
cell membrane;
cd40 nvs ... See more keywords
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Published in 2022 at "Biotechnology advances"
DOI: 10.1016/j.biotechadv.2022.107917
Abstract: Chimeric antigen receptor (CAR) technology, and CAR-T cells in particular, have emerged as a new and powerful tool in cancer immunotherapy since demonstrating efficacy against several hematological malignancies. However, despite encouraging clinical results of CAR-T…
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Keywords:
cell therapies;
car engineered;
novel car;
engineered cell ... See more keywords
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Published in 2023 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c07972
Abstract: α-Arbutin is extensively used in cosmetic industries. The lack of highly active enzymes and the cytotoxicity of hydroquinone limit the biosynthesis of α-arbutin. In this study, a whole-cell biocatalytic approach based on enzyme engineering and…
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Keywords:
cell;
engineered cell;
cell modification;
whole cell ... See more keywords
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Published in 2022 at "Biomaterials science"
DOI: 10.1039/d2bm01472f
Abstract: Craniomaxillofacial bone defects seriously affect the physical and mental health of patients. Bone marrow mesenchymal stem cells (BMSCs) are "gold standard" cells used for bone repair. However, the collection of BMSCs is invasive, and the…
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Keywords:
engineered cell;
circ cttn;
overexpression circular;
bone ... See more keywords
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Published in 2023 at "Science Advances"
DOI: 10.1126/sciadv.adf3700
Abstract: T cell engineering has changed the landscape of cancer immunotherapy. Chimeric antigen receptor T cells have demonstrated a remarkable efficacy in the treatment of B cell malignancies in hematology. However, their clinical impact on solid…
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Keywords:
engineered cell;
cell;
cell therapy;
therapy solid ... See more keywords
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Published in 2022 at "Journal for Immunotherapy of Cancer"
DOI: 10.1136/jitc-2021-003486
Abstract: Despite promising clinical results in a small subset of malignancies, therapies based on engineered chimeric antigen receptor and T-cell receptor T cells are associated with serious adverse events, including cytokine release syndrome and neurotoxicity. These…
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Keywords:
engineered cell;
cell;
evolve predicting;
predicting engineered ... See more keywords
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Published in 2019 at "Cancer Research"
DOI: 10.1158/1538-7445.sabcs18-2584
Abstract: Introduction: Exosomes (commonly known as extracellular vesicles) have generated tremendous interest for the therapeutic and diagnostic applications for oncology and other diseases. Specifically, exosome molecular cargo (proteins, nucleic acid, and small molecules) profiling have been…
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Keywords:
reference standards;
exo ref;
engineered cell;
cell ... See more keywords
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Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.3019
Abstract: 3019Background: Engineered T-cell therapy is an emerging treatment for hematological cancers. In epithelial cancers, its study has been limited. Human papillomavirus (HPV)-16+ epithelial cancers co...
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Keywords:
cell therapy;
hpv;
epithelial cancers;
engineered cell ... See more keywords
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Published in 2023 at "Neural Regeneration Research"
DOI: 10.4103/1673-5374.363828
Abstract: Background: The most widely employed approach by cell biologists to performing in vitro cell culture assays is the one using 2D plastic culture ware systems, which allows reproducibility and ease of use. Moreover, this method…
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Keywords:
engineered cell;
cell;
models era;
cell microenvironments ... See more keywords