Inhibition of Rho-associated kinases suppresses cardiac myofibroblast function in engineered connective and heart muscle tissues.
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DOI: 10.1016/j.yjmcc.2019.06.015
Abstract: Cardiac fibrosis is a hallmark of heart failure for which there is no effective pharmacological therapy. By genetic modification and in vivo inhibitor approaches it was suggested that the Rho-associated kinases (ROCK1 and ROCK2) are… read more here.
Keywords: heart; engineered connective; inhibition; rho associated ... See more keywords