Increased Throughput of Combined Stability Testing and Metabolite Identification Using a Sample Multiplexing Strategy for the Optimization of Engineered Cyclic Peptide Drugs.
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DOI: 10.1021/jasms.5c00113
Abstract: Engineered cyclic peptides (ECPs) have been in the spotlight as novel drug modalities for challenging therapeutic targets. Oral delivery of engineered cyclic peptides benefits from ease of administration. However, one of the main hurdles in… read more here.
Keywords: stability; peptide drugs; engineered cyclic; multiplexing strategy ... See more keywords