Engineered Design of a Mesoporous Silica Nanoparticle-Based Nanocarrier for Efficient mRNA Delivery in Vivo.
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DOI: 10.1021/acs.nanolett.2c04486
Abstract: We have developed tailor-designed mesoporous silica nanoparticles (MSNPs) specifically for delivering mRNA. Our unique assembly protocol involves premixing mRNA with a cationic polymer and then electrostatically binding it to the MSNP surface. Since the key… read more here.
Keywords: mesoporous silica; engineered design; mrna delivery; design mesoporous ... See more keywords