Simultaneous production of 2′‐fucosyllactose and difucosyllactose by engineered Escherichia coli with high secretion efficiency
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology Journal"
DOI: 10.1002/biot.202100629
Abstract: Difucosyllactose (Di‐FL) has strong antimicrobial activity against various pathogens, including group B Streptococcus, identified as the leading cause of neonatal sepsis. In this study, we sought to develop Escherichia coli as a microbial cell factory… read more here.
Keywords: fucosyllactose difucosyllactose; difucosyllactose engineered; escherichia coli; simultaneous production ... See more keywords
L‐Fucose production by engineered Escherichia coli
Sign Up to like & getrecommendations! Published in 2019 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.26907
Abstract: L‐Fucose (6‐deoxy‐L‐galactose) is a major constituent of glycans and glycolipids in mammals. Fucosylation of glycans can confer unique functional properties and may be an economical way to manufacture L‐fucose. Research can extract L‐fucose directly from… read more here.
Keywords: engineered escherichia; production; escherichia coli; fucose production ... See more keywords
Extending the shikimate pathway for microbial production of maleate from glycerol in engineered Escherichia coli
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.27700
Abstract: Maleate is one of the most important unsaturated four‐carbon dicarboxylic acids. It serves as an attractive building block in cosmetic, polymer, and pharmaceutical industries. Currently, industrial production of maleate relies mainly on chemical synthesis using… read more here.
Keywords: engineered escherichia; production; escherichia coli; maleate ... See more keywords
Improved production of heme using metabolically engineered Escherichia coli
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.28194
Abstract: Heme has recently attracted much attention due to its promising applications in the food and healthcare industries. However, the current titers and productivities of heme produced by recombinant microorganisms are not high enough for a… read more here.
Keywords: heme; production heme; escherichia coli; engineered escherichia ... See more keywords
Production of zinc protoporphyrin IX by metabolically engineered Escherichia coli
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.28195
Abstract: Zinc protoporphyrin IX (ZnPPIX) has been considered as a promising red colorant for food industries as well as an anticancer drug. However, bio‐based production of ZnPPIX from a renewable carbon source has not been reported… read more here.
Keywords: engineered escherichia; metabolically engineered; production; zinc protoporphyrin ... See more keywords
Improved production of Humira antibody in the genetically engineered Escherichia coli SHuffle, by co-expression of human PDI-GPx7 fusions
Sign Up to like & getrecommendations! Published in 2020 at "Applied Microbiology and Biotechnology"
DOI: 10.1007/s00253-020-10920-5
Abstract: Abstract Microbial production of antibodies offers the promise of cheap, fast, and efficient production of antibodies at an industrial scale. Limiting this capacity in prokaryotes is the absence of the post-translational machinery, present in dedicated… read more here.
Keywords: genetically engineered; engineered escherichia; production; antibody ... See more keywords
Co-production of ethanol-hydrogen by genetically engineered Escherichia coli in sustainable biorefineries for lignocellulosic ethanol production
Sign Up to like & getrecommendations! Published in 2021 at "Chemical Engineering Journal"
DOI: 10.1016/j.cej.2020.126829
Abstract: Abstract This work shows the impact of the hydrogen and ethanol co-production –via dark fermentation– using a genetically engineered Escherichia coli in the environmental and economic sustainability of a lignocellulose-based biorefinery. Wheat straw (WS) and… read more here.
Keywords: genetically engineered; engineered escherichia; production; escherichia coli ... See more keywords
A systematically chromosomally engineered Escherichia coli efficiently produces butanol.
Sign Up to like & getrecommendations! Published in 2017 at "Metabolic engineering"
DOI: 10.1016/j.ymben.2017.10.014
Abstract: Biotechnological production of butanol in heterologous hosts has recently attracted many interests. Of the heterologous hosts investigated to date, engineered Escherichia coli has shown a superior butanol yield than the natural butanol-producing clostridial strains. However,… read more here.
Keywords: systematically chromosomally; butanol; engineered escherichia; escherichia coli ... See more keywords
Exceeding the theoretical fermentation yield in mixotrophic Rubisco-based engineered Escherichia coli.
Sign Up to like & getrecommendations! Published in 2018 at "Metabolic engineering"
DOI: 10.1016/j.ymben.2018.04.018
Abstract: Rubisco-based engineered Escherichia coli MZLFB (E. coli BL21(DE3) Δzwf, Δldh, Δfrd) containing heterologous phosphoribulokinase (Prk) and Ribulose-1,5- bisphosphate carboxylase/oxygenase (Rubisco) was constructed for the mixotrophic growth. However, in situ CO2 recycling was hindered by clogs… read more here.
Keywords: based engineered; engineered escherichia; ctv; yield ... See more keywords
High-yield production of L-valine in engineered Escherichia coli by a novel two-stage fermentation.
Sign Up to like & getrecommendations! Published in 2020 at "Metabolic engineering"
DOI: 10.1016/j.ymben.2020.09.007
Abstract: L-valine is an essential amino acid and an important amino acid in the food and feed industry. The relatively low titer and low fermentation yield currently limit the large-scale application of L-valine. Here, we constructed… read more here.
Keywords: engineered escherichia; valine; two stage; escherichia coli ... See more keywords
De Novo Biosynthesis of Methyl Cinnamate in Engineered Escherichia coli.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c02638
Abstract: Methyl cinnamate with a fruity balsamic odor is an important fragrance ingredient in perfumes and cosmetics. Chemical processes are currently the only means of producing methyl cinnamate. But consumers prefer natural flavors. Therefore, it is… read more here.
Keywords: novo biosynthesis; methyl cinnamate; escherichia coli; engineered escherichia ... See more keywords