Genetically Engineered Exosomes as a Potential Regulator of Th1 Cells Response in Rheumatoid Arthritis.
Sign Up to like & getrecommendations! Published in 2023 at "Biopreservation and biobanking"
DOI: 10.1089/bio.2022.0003
Abstract: Background: Rheumatoid arthritis is a long-lasting inflammatory disease that usually involves joints, but it can also affect other organs, including the skin and lungs. In this case, it is important to maintain a balance between… read more here.
Keywords: derived exosomes; rheumatoid arthritis; mir 146a; engineered exosomes ... See more keywords
EXTH-38. ENGINEERED EXOSOMES FOR THERAPEUTIC GENE DELIVERY IN BRAIN TUMORS
Sign Up to like & getrecommendations! Published in 2019 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noz175.370
Abstract: The poor outcome of patients with glioblastoma (GBM) is at least partly due to the inability to deliver therapeutic agents to the tumor. We have shown that exosomes, naturally occurring nano-size extracellular vesicles, are capable… read more here.
Keywords: therapeutic gene; engineered exosomes; delivery; brain tumors ... See more keywords
Engineered Exosomes Loaded with miR-563 Inhibit Lung Cancer Growth
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Oncology"
DOI: 10.1155/2022/6141857
Abstract: The malignancy of lung cancer (LC) is serious in the world. Exosomes are well-known natural nanovesicles, which are reported to have the potential to carry functional miRNAs as natural carriers and deliver chemotherapeutic drugs. However,… read more here.
Keywords: engineered exosomes; lung cancer; tumor; mir 563 ... See more keywords
Abstract 1139: CD206 positive M2-macrophage targeting engineered exosomes as a potential diagnostic and therapeutic tool
Sign Up to like & getrecommendations! Published in 2019 at "Tumor Biology"
DOI: 10.1158/1538-7445.am2019-1139
Abstract: Tumor initiation and evolution is driven by the reciprocal actions between stromal and immune cells within the tumor microenvironment (TME). Tumor-associated macrophages (TAMs) specifically M2-macrophages, a critical component of TME; participate in immune suppression, epithelial… read more here.
Keywords: 111in oxine; cd206 positive; positive macrophage; engineered exosomes ... See more keywords
Engineered Exosomes-Mediated Transfer of hsa-miR-320a Overcomes Chemoresistance in Cervical Cancer Cells via Targeting MCL1
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.883445
Abstract: In cervical cancer (CC), cisplatin resistance greatly restricts the application in clinical. Here, we report that engineered exosomes-mediated transfer of hsa-miR-320a overcomes chemoresistance in cervical cancer cells via targeting Myeloid Cell Leukemia Sequence 1 (MCL1).… read more here.
Keywords: cervical cancer; 320a overcomes; engineered exosomes; ddp ... See more keywords
Anti-Cancer Vaccine for HPV-Associated Neoplasms: Focus on a Therapeutic HPV Vaccine Based on a Novel Tumor Antigen Delivery Method Using Endogenously Engineered Exosomes
Sign Up to like & getrecommendations! Published in 2019 at "Cancers"
DOI: 10.3390/cancers11020138
Abstract: Some human papillomavirus (HPV) genotypes are universally recognized as major etiological agents not only of ano-genital tumors but also of head and neck cancers, which show increasing incidence. The evaluation of current and future therapeutic… read more here.
Keywords: novel tumor; hpv; antigen; vaccine ... See more keywords
Emerging role of engineered exosomes in nonalcoholic fatty liver disease
Sign Up to like & getrecommendations! Published in 2023 at "World Journal of Hepatology"
DOI: 10.4254/wjh.v15.i3.386
Abstract: Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease worldwide. NAFLD comprises a continuum of liver abnormalities from nonalcoholic fatty liver to nonalcoholic steatohepatitis, and can even lead to cirrhosis and liver… read more here.
Keywords: nonalcoholic fatty; fatty liver; engineered exosomes; emerging role ... See more keywords