Surface expression of anti‐CD3scfv stimulates locoregional immunotherapy against hepatocellular carcinoma depending on the E1A‐engineered human umbilical cord mesenchymal stem cells
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Cancer"
DOI: 10.1002/ijc.30846
Abstract: Tumor antigens is at the core of cancer immunotherapy, however, the ideal antigen selection is difficult especially in poorly immunogenic tumors. In this study, we designed a strategy to modify hepatocellular carcinoma (HCC) cells by… read more here.
Keywords: anti cd3scfv; hepatocellular carcinoma; tumor; cd3scfv ... See more keywords
Engineered Human Gastrointestinal Cultures to Study the Microbiome and Infectious Diseases
Sign Up to like & getrecommendations! Published in 2018 at "Cellular and Molecular Gastroenterology and Hepatology"
DOI: 10.1016/j.jcmgh.2017.12.001
Abstract: New models to study the intestine are key to understanding intestinal diseases and developing novel treatments. Intestinal organ-like culture systems (organoids and enteroids) have substantially advanced the study of the human gastrointestinal tract. Stem cell–derived… read more here.
Keywords: gastrointestinal cultures; human gastrointestinal; infectious diseases; cultures study ... See more keywords
Rapid generation of functional engineered 3D human neuronal assemblies: network dynamics evaluated by micro-electrodes arrays
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DOI: 10.1088/1741-2552/ac3e02
Abstract: Objective. In this work we adapted a protocol for the fast generation of human neurons to build 3D neuronal networks with controlled structure and cell composition suitable for systematic electrophysiological investigations. Approach. We used biocompatible… read more here.
Keywords: rapid generation; generation functional; neuronal networks; functional engineered ... See more keywords
Engineered human immunoglobulin anti-yellow fever virus monoclonal antibodies to treat severe yellow fever.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of travel medicine"
DOI: 10.1093/jtm/taaa164
Abstract: Teaser A new engineered human immunoglobulin (Ig)G anti-yellow fever virus monoclonal antibody suggested potential clinical benefit in Phase 1a and 1b clinical trial. read more here.
Keywords: yellow fever; fever; human immunoglobulin; immunoglobulin anti ... See more keywords