Engineered Protein-Au Bioplaster for Efficient Skin Tumor Therapy.
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DOI: 10.1002/adma.202110062
Abstract: Melanoma is the most lethal malignancy in skin cancer and may occur at any site and express melanocytes. Due to malignant melanoma's invasion and migration nature, conventional therapies make it challenging to remove the whole… read more here.
Keywords: tumor; therapy; skin tumor; tumor therapy ... See more keywords
Molecularly Engineered Protein Glues with Superior Adhesion Performance
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DOI: 10.1002/adma.202204590
Abstract: Naturally inspired proteins are investigated for the development of bioglues that combine adhesion performance and biocompatibility for biomedical applications. However, engineering such adhesives by rational design of the proteins at the molecular level is rarely… read more here.
Keywords: adhesion; molecularly engineered; engineered protein; adhesion performance ... See more keywords
Bionic Engineered Protein Coating Boosting Anti‐Biofouling in Complex Biological Fluids
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DOI: 10.1002/adma.202208824
Abstract: Implantable medical devices have been widely applied in diagnostics, therapeutics, organ restoration, and other biomedical areas, but often suffer from dysfunction and infections due to irreversible biofouling. Inspired by the self‐defensive “vine‐thorn” structure of climbing… read more here.
Keywords: biofouling; complex biological; engineered protein; surface ... See more keywords
Engineered protein nanodrug as an emerging therapeutic tool
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DOI: 10.1007/s12274-022-4103-2
Abstract: Functional proteins are the most versatile macromolecules. They can be obtained by extraction from natural sources or by genetic engineering technologies. The outstanding selectivity, specificity, binding activity, and biocompatibility endow engineered proteins with outstanding performance… read more here.
Keywords: emerging therapeutic; therapeutic tool; therapeutic proteins; engineered protein ... See more keywords
Engineered Protein Copolymers for Heparin Neutralization and Detection
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DOI: 10.1021/acs.biomac.2c01464
Abstract: Heparin is a widely applied anticoagulant agent. However, in clinical practice, it is of vital importance to reverse its anticoagulant effect to restore the blood-clotting cascade and circumvent side effects. Inspired by protein cages that… read more here.
Keywords: protein copolymers; engineered protein; heparin neutralization; detection ... See more keywords