Persistence of adoptively transferred T cells with a kinetically engineered IL-2 receptor agonist
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-019-12901-3
Abstract: Interleukin-2 (IL-2) is a component of most protocols of adoptive cell transfer (ACT) therapy for cancer, but is limited by short exposure and high toxicities. NKTR-214 is a kinetically-engineered IL-2 receptor βγ (IL-2Rβγ)-biased agonist consisting… read more here.
Keywords: nktr 214; transferred cells; act; adoptively transferred ... See more keywords