Engineered skeletal muscle recapitulates human muscle development, regeneration and dystrophy
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.13094
Abstract: Human pluripotent stem cell‐derived muscle models show great potential for translational research. Here, we describe developmentally inspired methods for the derivation of skeletal muscle cells and their utility in skeletal muscle tissue engineering with the… read more here.
Keywords: engineered skeletal; regeneration dystrophy; skeletal muscle; muscle ... See more keywords
Transplantation of HGF gene-engineered skeletal myoblasts improve infarction recovery in a rat myocardial ischemia model
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0175807
Abstract: Background Skeletal myoblast transplantation seems a promising approach for the repair of myocardial infarction (MI). However, the low engraftment efficacy and impaired angiogenic ability limit the clinical efficiency of the myoblasts. Gene engineering with angiogenic… read more here.
Keywords: hgf gene; engineered skeletal; skeletal myoblasts; infarction ... See more keywords
Scalable 3D Printed Molds for Human Tissue Engineered Skeletal Muscle
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2019.00020
Abstract: Tissue engineered skeletal muscle allows investigation of the cellular and molecular mechanisms that regulate skeletal muscle pathology. The fabricated model must resemble characteristics of in vivo tissue and incorporate cost-effective and high content primary human… read more here.
Keywords: human tissue; skeletal muscle; muscle; engineered skeletal ... See more keywords