Development of an innervated tissue-engineered skin with human sensory neurons and Schwann cells differentiated from iPS cells.
Sign Up to like & getrecommendations! Published in 2018 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2018.10.011
Abstract: Cutaneous innervation is increasingly recognized as a major element of skin physiopathology through the neurogenic inflammation driven by neuropeptides that are sensed by endothelial cells and the immune system. To investigate this process in vitro,… read more here.
Keywords: innervated tissue; skin; engineered skin; sensory neurons ... See more keywords
Feasibility of repairing skin defects by VEGF165 gene-modified iPS-HFSCs seeded on a 3D printed scaffold containing astragalus polysaccharide.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of cellular and molecular medicine"
DOI: 10.1111/jcmm.17800
Abstract: The preparation of biodegradable scaffolds loaded with cells and cytokine is a feature of tissue-engineered skin. IPSCs-based tissue-engineered skin treatment for wound repair is worth exploring. Healthy human skin fibroblasts were collected and reprogrammed into… read more here.
Keywords: vegf165 gene; tissue engineered; gene modified; engineered skin ... See more keywords
Engineered skin bacteria induce antitumor T cell responses against melanoma
Sign Up to like & getrecommendations! Published in 2023 at "Science"
DOI: 10.1126/science.abp9563
Abstract: Certain bacterial colonists induce a highly specific T cell response. A hallmark of this encounter is that adaptive immunity develops preemptively, in the absence of an infection. However, the functional properties of colonist-induced T cells… read more here.
Keywords: cell; tumor antigens; skin bacteria; engineered skin ... See more keywords
Expression of C4.4A in an In Vitro Human Tissue-Engineered Skin Model
Sign Up to like & getrecommendations! Published in 2017 at "BioMed Research International"
DOI: 10.1155/2017/2403072
Abstract: A multi-LU-domain-containing protein denoted C4.4A exhibits a tightly regulated membrane-associated expression in the suprabasal layers of stratified squamous epithelia such as skin and the esophagus, and the expression of C4.4A is dysregulated in various pathological… read more here.
Keywords: vitro human; engineered skin; tissue; expression ... See more keywords
Tissue engineered skin products in research and therapeutic applications.
Sign Up to like & getrecommendations! Published in 2022 at "Orvosi hetilap"
DOI: 10.1556/650.2022.32330
Abstract: Összefoglaló. A bőrpótlóknak mind a klinikumban, mind a gyógyszerkutatásokban kiemelt szerepük van. Ezek a kezdetleges mesterséges bőrszövetek segíthetik a bőr regenerálódását, modellezhetik a főbb funkciókat, de megvannak a korlátaik is, mechanikailag sérülékenyek, és nem tartósak.… read more here.
Keywords: skin; tissue engineered; engineered skin; therapeutic applications ... See more keywords
Human fetal skin derived merkel cells display distinctive characteristics in vitro and in bio-engineered skin substitutes in vivo
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.983870
Abstract: Human skin contains specialized neuroendocrine Merkel cells responsible for fine touch sensation. In the present study, we performed in-depth analysis of Merkel cells in human fetal back skin. We revealed that these Merkel cells expressed… read more here.
Keywords: merkel cells; skin; fetal skin; human fetal ... See more keywords
Engineered Skin Substitute Regenerates the Skin with Hair Follicle Formation
Sign Up to like & getrecommendations! Published in 2021 at "Biomedicines"
DOI: 10.3390/biomedicines9040400
Abstract: Currently, engineered skin substitutes (ESS) are unable to regenerate cutaneous appendages. Recent studies have shown that skin-derived precursors (SKPs), which are extensively available, have the potential to induce hair follicle neogenesis. Here, we demonstrate that… read more here.
Keywords: hair follicle; skin substitute; hair; engineered skin ... See more keywords
Advances in Skin Regeneration Using Tissue Engineering
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms18040789
Abstract: Tissue engineered skin substitutes for wound healing have evolved tremendously over the last couple of years. New advances have been made toward developing skin substitutes made up of artificial and natural materials. Engineered skin substitutes… read more here.
Keywords: skin substitute; engineered skin; tissue; skin regeneration ... See more keywords