Effects of different mechanisms on antimicrobial resistance in Acinetobacter baumannii: A strategic system for the screening and activity testing of new antibiotics.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of antimicrobial agents"
DOI: 10.1016/j.ijantimicag.2020.105918
Abstract: A total of 50 engineered strains with various resistance mechanisms from two fully susceptible strains, Acinetobacter baumannii KAB1544 and ATCC 17978, were constructed by in-frame deletion, site-directed mutagenesis and plasmid transformation. These strains included 31… read more here.
Keywords: system; engineered strains; resistance mechanisms; resistance ... See more keywords
Use of CRISPR‐Cas tools to engineer Trichoderma species
Sign Up to like & getrecommendations! Published in 2022 at "Microbial Biotechnology"
DOI: 10.1111/1751-7915.14126
Abstract: Given their lignocellulose degradability and biocontrol activities, fungi of the ubiquitously distributed genus Trichoderma have multiple industrial and agricultural applications. Genetic manipulation plays a valuable role in tailoring novel engineered strains with enhanced target traits.… read more here.
Keywords: cas tools; genetic manipulation; use crispr; cas ... See more keywords
Construction of industrial baker's yeast with high level of cAMP.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of food biochemistry"
DOI: 10.1111/jfbc.12846
Abstract: Cyclic adenosine monophosphate (cAMP) plays an important role in modulating the activity of microbe cell. In this study, PKA (protein kinase A) activity was weakened through truncation of TPK2 promoter (-150 bp and -300 bp) and gene… read more here.
Keywords: activity; level camp; engineered strains; high level ... See more keywords