Transient Support from Fibroblasts is Sufficient to Drive Functional Vascularization in Engineered Tissues.
Sign Up to like & getrecommendations! Published in 2020 at "Advanced functional materials"
DOI: 10.1002/adfm.202003777
Abstract: Formation of capillary blood vasculature is a critical requirement for native as well as engineered organs and can be induced in vitro by co-culturing endothelial cells with fibroblasts. However, whether these fibroblasts are required only… read more here.
Keywords: fibroblasts sufficient; engineered tissues; support fibroblasts; morphogenesis ... See more keywords
Using Decellularization/Recellularization Processes to Prepare Liver and Cardiac Engineered Tissues.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1246-0_7
Abstract: Tissue engineering provides unique opportunities for disease modeling, drug testing, and regenerative medicine applications. The use of cell-seeded scaffolds to promote tissue development is the hallmark of the tissue engineering. Among the different types of… read more here.
Keywords: decellularization recellularization; engineered tissues; using decellularization; tissue ... See more keywords
Integrated approaches to spatiotemporally directing angiogenesis in host and engineered tissues.
Sign Up to like & getrecommendations! Published in 2018 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2018.01.017
Abstract: The field of tissue engineering has turned towards biomimicry to solve the problem of tissue oxygenation and nutrient/waste exchange through the development of vasculature. Induction of angiogenesis and subsequent development of a vascular bed in… read more here.
Keywords: vascularization; angiogenesis; engineered tissues; tissue ... See more keywords
Human Pluripotent Stem Cell-Derived Engineered Tissues: Clinical Considerations.
Sign Up to like & getrecommendations! Published in 2018 at "Cell stem cell"
DOI: 10.1016/j.stem.2018.01.015
Abstract: The combined power of human pluripotent stem cells and tissue engineering promises to revolutionize medicine by building tissue patches and artificial replacement organs for patients battling diverse diseases. Here, we articulate some big questions that… read more here.
Keywords: human pluripotent; engineered tissues; stem cell; pluripotent stem ... See more keywords
Stimulating Extracellular Vesicles Production from Engineered Tissues by Mechanical Forces.
Sign Up to like & getrecommendations! Published in 2021 at "Nano letters"
DOI: 10.1021/acs.nanolett.0c04834
Abstract: Extracellular vesicles (EVs) have emerged as a promising strategy to promote tissue regeneration. However, overcoming the low EV production yield remains a big challenge in translating EV-based therapies to the clinical practice. Current EV production… read more here.
Keywords: extracellular vesicles; production; engineered tissues; stimulating extracellular ... See more keywords
Engineering Spatiotemporal Control in Vascularized Tissues
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineering"
DOI: 10.3390/bioengineering9100555
Abstract: A major challenge in engineering scalable three-dimensional tissues is the generation of a functional and developed microvascular network for adequate perfusion of oxygen and growth factors. Current biological approaches to creating vascularized tissues include the… read more here.
Keywords: engineering spatiotemporal; vascularized tissues; control; spatiotemporal control ... See more keywords
A Bionic Testbed for Cardiac Ablation Tools
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232214444
Abstract: Bionic-engineered tissues have been proposed for testing the performance of cardiovascular medical devices and predicting clinical outcomes ex vivo. Progress has been made in the development of compliant electronics that are capable of monitoring treatment… read more here.
Keywords: ablation; bionic testbed; pressure; engineered tissues ... See more keywords