Articles with "engineered toxin" as a keyword



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Abstract 2278: CTLA-4 targeted engineered toxin bodies designed to deplete regulatory T cells (Tregs)

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Published in 2020 at "Immunology"

DOI: 10.1158/1538-7445.am2020-2278

Abstract: Tumor resident regulatory T cells (Tregs) are important mediators of an immunosuppressive tumor microenvironment (TME) promoting tumor immune evasion. The presence of Tregs, and a higher ratio of Tregs to effector T cells in the… read more here.

Keywords: toxin bodies; ctla; regulatory cells; cells tregs ... See more keywords