Immunomodulation Strategies for the Successful Regeneration of a Tissue‐Engineered Vascular Graft
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202200045
Abstract: Cardiovascular disease leads to the highest morbidity worldwide. There is an urgent need to solve the lack of a viable arterial graft for patients requiring coronary artery bypass surgery. The current gold standard is to… read more here.
Keywords: regeneration; engineered vascular; vascular graft; tissue engineered ... See more keywords
Monitoring the Remodeling of Biohybrid Tissue-Engineered Vascular Grafts by Multimodal Molecular Imaging.
Sign Up to like & getrecommendations! Published in 2022 at "Advanced science"
DOI: 10.1002/advs.202105783
Abstract: Tissue-engineered vascular grafts (TEVGs) with the ability to grow and remodel open new perspectives for cardiovascular surgery. Equipping TEVGs with synthetic polymers and biological components provides a good compromise between high structural stability and biological… read more here.
Keywords: molecular imaging; monitoring remodeling; vascular grafts; engineered vascular ... See more keywords
Selection of different endothelialization modes and different seed cells for tissue-engineered vascular graft
Sign Up to like & getrecommendations! Published in 2021 at "Bioactive Materials"
DOI: 10.1016/j.bioactmat.2020.12.021
Abstract: Tissue-engineered vascular grafts (TEVGs) have enormous potential for vascular replacement therapy. However, thrombosis and intimal hyperplasia are important problems associated with TEVGs especially small diameter TEVGs ( read more here.
Keywords: endothelialization; seed; tissue engineered; seed cells ... See more keywords
Optimization of oxygen transport within a tissue engineered vascular graft model using embedded micro-channels inspired by vasa vasorum
Sign Up to like & getrecommendations! Published in 2018 at "Chemical Engineering Science"
DOI: 10.1016/j.ces.2018.02.044
Abstract: Abstract Tissue Engineered Vascular Graft (TEVG) is a promising treatment for cardiovascular diseases because of its potential for repair and long-term patency. However, the quality and preparation time to achieve a mature TEVG has limited… read more here.
Keywords: oxygen; graft; transport; model ... See more keywords
Engineered 3D vascular and neuronal networks in a microfluidic platform
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-23512-1
Abstract: Neurovascular coupling plays a key role in the pathogenesis of neurodegenerative disorders including motor neuron disease (MND). In vitro models provide an opportunity to understand the pathogenesis of MND, and offer the potential for drug… read more here.
Keywords: microfluidic platform; vascular neuronal; platform; networks microfluidic ... See more keywords
Tissue engineered vascular grafts: current state of the field
Sign Up to like & getrecommendations! Published in 2017 at "Expert Review of Medical Devices"
DOI: 10.1080/17434440.2017.1324293
Abstract: ABSTRACT Introduction: Conventional synthetic vascular grafts are limited by the inability to remodel, as well as issues of patency at smaller diameters. Tissue-engineered vascular grafts (TEVGs), constructed from biologically active cells and biodegradable scaffolds have… read more here.
Keywords: state field; grafts current; vascular grafts; current state ... See more keywords
Simultaneous intraluminal imaging of tissue autofluorescence and eGFP-labeled cells in engineered vascular grafts inside a bioreactor.
Sign Up to like & getrecommendations! Published in 2019 at "Methods and applications in fluorescence"
DOI: 10.1088/2050-6120/ab4342
Abstract: The growing demand for tissue engineered vascular grafts (TEVG) motivates the development of optimized fabrication and monitoring procedures. Bioreactors which provide physiologically-relevant conditions are important for improving holistic TEVG properties and performance. Herein we describe… read more here.
Keywords: intraluminal imaging; vascular grafts; tissue; inside bioreactor ... See more keywords
Midterm results of pulmonary artery plasty with in vivo tissue-engineered vascular grafts.
Sign Up to like & getrecommendations! Published in 2021 at "Interactive cardiovascular and thoracic surgery"
DOI: 10.1093/icvts/ivab019
Abstract: We evaluated the application of in vivo tissue-engineered vascular graft (in vivo TEVG) in pulmonary artery (PA) reconstruction as a substitute for autologous pericardium. From July 2017 to April 2020, 4 patients (male:female = 2:2) with major… read more here.
Keywords: reconstruction; vivo; tissue engineered; pulmonary artery ... See more keywords
Spontaneous reversal of stenosis in tissue-engineered vascular grafts
Sign Up to like & getrecommendations! Published in 2020 at "Science Translational Medicine"
DOI: 10.1126/scitranslmed.aax6919
Abstract: Computational modeling and ovine data reveal spontaneous reversal of early tissue-engineered vascular graft stenosis, with clinical implications. Lessons in graft remodeling Tissue-engineered grafts have the capacity to grow and remodel after implantation, which could confer… read more here.
Keywords: graft; tissue engineered; stenosis; early stenosis ... See more keywords
Modifications of the mechanical properties of in vivo tissue-engineered vascular grafts by chemical treatments for a short duration
Sign Up to like & getrecommendations! Published in 2021 at "PLoS ONE"
DOI: 10.1371/journal.pone.0248346
Abstract: In vivo tissue-engineered vascular grafts constructed in the subcutaneous spaces of graft recipients have functioned well clinically. Because the formation of vascular graft tissues depends on several recipient conditions, chemical pretreatments, such as dehydration by… read more here.
Keywords: short duration; tissue; mechanical properties; tissue engineered ... See more keywords
Tissue engineered vascular grafts for pediatric cardiac surgery.
Sign Up to like & getrecommendations! Published in 2018 at "Translational pediatrics"
DOI: 10.21037/tp.2018.02.01
Abstract: New technologies and science have contributed to improved surgical outcomes in patients with congenital cardiovascular diseases. However, current materials display shortcomings, such as risk of infection and lack of growth capacity when applied to the… read more here.
Keywords: vascular grafts; tissue; grafts pediatric; pediatric cardiac ... See more keywords