Engineering of a Baeyer-Villiger monooxygenase reveals key residues for the asymmetric oxidation of omeprazole sulfide.
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DOI: 10.1039/d2cc04161h
Abstract: The structure-guided engineering of a BVMO from Rhodococcus aetherivorans (RaBVMO) was performed for its asymmetric sulfoxidation activity toward omeprazole sulfide. Based on the structural model of RaBVMO, key residues that line the substrate entrance tunnel… read more here.
Keywords: key residues; omeprazole sulfide; activity; engineering baeyer ... See more keywords