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Published in 2023 at "Small"
DOI: 10.1002/smll.202206357
Abstract: Engineering catalytically active sites have been a challenge so far and often relies on optimization of synthesis routes, which can at most provide quantitative enhancement of active facets, however, cannot provide control over choosing orientation,…
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Keywords:
active sites;
engineering catalytically;
geometry;
catalytically active ... See more keywords
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Published in 2017 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.6b12637
Abstract: Breaking and forming peptidyl bonds are fundamental biochemical reactions in protein chemistry. Unlike proteases that are abundantly available, fast-acting ligases are rare. OaAEP1 is an enzyme isolated from the cyclotide-producing plant oldenlandia affinis that displayed…
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Keywords:
protein;
catalytically efficient;
enzyme;
structure ... See more keywords